机构:[1]Department of Rehabilitation Medicine of Xuanwu Hospital,, Beijing, China康复医学科首都医科大学宣武医院[2]Department of Radiology,Xuanwu Hospital, Capital Medical University, Beijing, China放射科首都医科大学宣武医院[3]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China神经外科首都医科大学宣武医院
Objective: To investigate the impact of ventriculoperitoneal shunting during clinical rehabilitation of chronic normal pressure hydrocephalus patients with disorders of consciousness following aneurysmal subarachnoid haemorrhage. Design: Cross-sectional study. Patients and methods: Thirty-five patients with disorders of consciousness following aneurysmal subarachnoid haemorrhage who had undergone ventriculoperitoneal shunting for chronic normal pressure hydrocephalus were compared with 16 matched controls with no ventriculoperitoneal shunting. Data from clinical examinations, rehabilitation assessments and computed tomography scans (to exclude other diseases that can cause ventricular enlargement) were analysed. All the patients with disorders of consciousness underwent neurorehabilitation. Consciousness was measured on the Glasgow Coma Scale. The cella media index was calculated as the change in size of the lateral ventricles (prior to ventriculoperitoneal shunting and/or rehabilitation, and 1 and 3 months after shunting and/or rehabilitation). The short-term outcome of treatment was assessed at 3 months using the Glasgow Outcome Scale. Results: Twenty-four out of 35 patients with disorders of consciousness recovered gradually after ventriculoperitoneal shunting and rehabilitation. There was a significant difference in the Glasgow Coma Scale between ventriculoperitoneal shunting and control groups at both 1 and 3 months (F=19.29, p<0.01). Significant differences were also observed between the 2 groups in the cella media index at 1 and 3 months (F=15.03, p<0.01). The Glasgow Outcome Scale of the ventriculoperitoneal shunting group was significantly higher than that of the control group (p<0.01, r=0.55) 3 months after shunting and/or rehabilitation. Conclusion: Chronic normal pressure hydrocephalus during rehabilitation is a serious and previously unrecognized medical condition, which influences consciousness in patients following an aneurysmal subarachnoid haemorrhage. However, the condition can be treated by ventriculoperitoneal shunting, which helps some patients with disorders of consciousness to regain consciousness.
基金:
the National Natural Science Foundation of China (grant numbers 81171024 and 30770714),
the Natural Science Foundation of Beijing (grant number 7102075)
the Ministry of Organization of the Beijing government (grant number 20071D0501800243).
第一作者机构:[1]Department of Rehabilitation Medicine of Xuanwu Hospital,, Beijing, China[*1]International Collaboration on Repair Discoveries (ICORD), University of British Columbia (UBC), 818 West 10th Avenue, Vancouver, Canada, V5Z 1M 9[*2]Department of Rehabilitation Medicine of Xuanwu Hospital, Capital Medical University, Beijing, China, 100053.
通讯作者:
通讯机构:[*1]International Collaboration on Repair Discoveries (ICORD), University of British Columbia (UBC), 818 West 10th Avenue, Vancouver, Canada, V5Z 1M 9[*2]Department of Rehabilitation Medicine of Xuanwu Hospital, Capital Medical University, Beijing, China, 100053.
推荐引用方式(GB/T 7714):
Zhen Chen ,Yanhui Yang ,Ge Chen ,et al.IMPACT OF VENTRICULOPERITONEAL SHUNTING ON CHRONIC NORMAL PRESSURE HYDROCEPHALUS IN CONSCIOUSNESS REHABILITATION[J].JOURNAL OF REHABILITATION MEDICINE.2014,46(9):876-881.doi:10.2340/16501977-1856.
APA:
Zhen Chen,,Yanhui Yang,,Ge Chen,,Maobin Wang,&Weiqun Song,.(2014).IMPACT OF VENTRICULOPERITONEAL SHUNTING ON CHRONIC NORMAL PRESSURE HYDROCEPHALUS IN CONSCIOUSNESS REHABILITATION.JOURNAL OF REHABILITATION MEDICINE,46,(9)
MLA:
Zhen Chen,,et al."IMPACT OF VENTRICULOPERITONEAL SHUNTING ON CHRONIC NORMAL PRESSURE HYDROCEPHALUS IN CONSCIOUSNESS REHABILITATION".JOURNAL OF REHABILITATION MEDICINE 46..9(2014):876-881