机构：[1]Department of Thoracic Cardiovascular Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, P.R. China血管外科心脏科（外科专业）首都医科大学宣武医院[2]Center for GERD, The Second Artillery General Hospital of Chinese People’s Liberation Army, Beijing, P.R. China
Aim. Chronic cough is the most common extra-esophageal manifestation of gastroesophageal reflux disease (GERD). This study aimed to retrospectively analyze outcomes in patients with GERD-related cough following laparoscopic Nissen fundoplication (LNF) and Stretta radiofrequency (RF) respectively. Methods. Medical charts of 83 patients with GERD-related cough that underwent LNF or Stretta RF between 2007 and 2012 were retrieved. Symptom scores (heartburn, regurgitation and cough) and proton pump inhibitors (PPIs) usages were evaluated. Results. A total of 83 patients with GERD-related cough underwent LNF (N.=35) and Stretta RF (N.=48), and were followed up 36.78 +/- 16.12 months (range 13-55 months). During the follow-up, the post-treatment scores were statistically lower as compared with the pre-treatment scores in both groups, while the cough improvement after Stretta was significantly lower than that after LNF (P<0.001). Besides, 27 (77.1%) patients achieved complete PPI therapy independence after LNF, comparing with 27 (65.1%) after Stretta (P<0.05). No significant differences in post-treatment complications were observed except for the abdominal distention. Conclusion. Even though laparoscopic Nissen fundoplication and Stretta are capable of controlling GERD-related cough effectively and safely in selected patients, laparoscopic Nissen fundoplication could improve more in symptoms and PPI elimination.
第一作者机构：[1]Department of Thoracic Cardiovascular Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, P.R. China
通讯作者：
通讯机构：[1]Department of Thoracic Cardiovascular Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, P.R. China[2]Center for GERD, The Second Artillery General Hospital of Chinese People’s Liberation Army, Beijing, P.R. China
推荐引用方式(GB/T 7714)：
Liang W. T.,Wu J. M.,Hu Z. W.,et al.Laparoscopic Nissen fundoplication is more effective in treating patients with GERD-related chronic cough than Stretta radiofrequency[J].MINERVA CHIRURGICA.2014,69(3):121-127.
APA：
Liang W. T.,Wu J. M.,Hu Z. W.,Wang Z. G.,Zhu G. C.&Zhang C..(2014).Laparoscopic Nissen fundoplication is more effective in treating patients with GERD-related chronic cough than Stretta radiofrequency.MINERVA CHIRURGICA,69,(3)
MLA：
Liang W. T.,et al."Laparoscopic Nissen fundoplication is more effective in treating patients with GERD-related chronic cough than Stretta radiofrequency".MINERVA CHIRURGICA 69..3(2014):121-127
