机构：[1]Xuan Wu Hospital, Capital Medical University, China (Xuan Wu Hospital) – America (Massachusetts General Hospital) Joint Institute of Neuroscience, Beijing, Geriatric Medical Research Center, Beijing, China首都医科大学宣武医院[2]Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, USA
The neurovascular unit is now well accepted as a conceptual framework for investigating the mechanisms of ischemic stroke. From a molecular and cellular perspective, three broad mechanisms may underlie stroke pathophysiology-excitotoxicity, oxidative stress and inflammation. To date, however, most investigations of these basic mechanisms have focused on neuronal responses. In this mini-review, we ask whether these mechanisms of excitotoxicity, oxidative stress and inflammation can also be examined in terms of non-neuronal interactions in the neurovascular unit, including the release of extracellular vesicles for cell-cell signaling.
基金：
the National Institutes of Health
the SUMITOMO Life Social Welfare Service Foundation
the National Natural Science Foundation of China (Grant No. 81200915)
the Beijing Natural Science Foundation
the China National Basic Research 973 Program
第一作者机构：[2]Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, USA
共同第一作者：
通讯作者：
通讯机构：[*1]Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, USA[*2]Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China
推荐引用方式(GB/T 7714)：
Y. Terasaki,Y. Liu,K. Hayakawa,et al.Mechanisms of Neurovascular Dysfunction in Acute Ischemic Brain[J].CURRENT MEDICINAL CHEMISTRY.2014,21(18):2035-2042.doi:10.2174/0929867321666131228223400.
APA：
Y. Terasaki,Y. Liu,K. Hayakawa,L.D. Pham,E.H. Lo...&K. Arai.(2014).Mechanisms of Neurovascular Dysfunction in Acute Ischemic Brain.CURRENT MEDICINAL CHEMISTRY,21,(18)
MLA：
Y. Terasaki,et al."Mechanisms of Neurovascular Dysfunction in Acute Ischemic Brain".CURRENT MEDICINAL CHEMISTRY 21..18(2014):2035-2042
：