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Non-pharmaceutical therapies for stroke: Mechanisms and clinical implications

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收录情况： ◇ SCIE

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机构： [a]Cerebrovascular Diseases Research Institute, Xuanwu Hospital of Capital Medical University, Beijing, Beijing 100053, China [b]The Vivian L. Smith Department of Neurosurgery, The University of Texas Medical School at Houston, Houston, TX 77030, USA [c]Shanghai Research Center for Acupuncture and Meridian, Shanghai 201203, China

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关键词： Non-pharmaceutical therapies Stroke Ischemia Neuroprotection

摘要：

Stroke is deemed a worldwide leading cause of neurological disability and death, however, there is currently no promising pharmacotherapy for acute ischemic stroke aside from intravenous or intra-arterial thrornbolysis. Yet because of the narrow therapeutic time window involved, thrombolytic application is very restricted in clinical settings. Accumulating data suggest that non-pharmaceutical therapies for stroke might provide new opportunities for stroke treatment. Here we review recent research progress in the mechanisms and clinical implications of non-pharmaceutical therapies, mainly including neuroprotective approaches such as hypothermia, ischemic/hypoxic conditioning, acupuncture, medical gases and transcranial laser therapy. In addition, we briefly summarize mechanical endovascular recanalization devices and recovery devices for the treatment of the chronic phase of stroke and discuss the relative merits of these devices. (c) 2014 Elsevier Ltd. All rights reserved.

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出版当年[2013]版：

大类 | 1 区

医学

小类 | 1 区神经科学

最新[2023]版

：

大类 | 2 区医学

小类 | 2 区神经科学

JCR分区：

出版当年[2012]版：

Q1 NEUROSCIENCES

最新[2023]版：

Q1 NEUROSCIENCES

影响因子： 6.7 最新[2023版] 8.7 最新五年平均 9.035 出版当年[2012版] 10.322 出版当年五年平均 8.874 出版前一年[2011版] 10.301 出版后一年[2013版]

第一作者：

第一作者机构： [a]Cerebrovascular Diseases Research Institute, Xuanwu Hospital of Capital Medical University, Beijing, Beijing 100053, China

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通讯作者：

通讯机构： [a]Cerebrovascular Diseases Research Institute, Xuanwu Hospital of Capital Medical University, Beijing, Beijing 100053, China [b]The Vivian L. Smith Department of Neurosurgery, The University of Texas Medical School at Houston, Houston, TX 77030, USA

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