机构：[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, P. R. China神经内科首都医科大学宣武医院[b]Department of Computer Science, University of Otago, Dunedin, New Zealand[c]Department of Neurology, Fu Xing Hospital, Capital Medical University, Beijing, P. R. China[d]Department of Geriatrics, Guangzhou Brain Hospital, Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong Province, P. R. China[e]Department of Neurology, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou Province, P. R. China[f]Department of Neurology, Third Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, P. R. China[g]Department of Neurology, First Hospital of Jilin University, Changchun, Jinlin Province, P. R. China[h]Department of Neurology, Fourth Hospital of Jilin University, Changchun, Jinlin Province, P. R. China[i]Department of Neurology, Beijing Geriatric Hospital, Beijing, P. R. China[j]National Center for Chronic and Noncommunicable Disease Control and Prevention, Beijing, P. R. China[k]Department of Neurology, Tongren Hospital, Capital Medical University, Beijing, P. R. China
Objective: The Chinese population has been aging rapidly and the country's economy has experienced exponential growth during the past three decades. The goal of this study was to estimate the changes in the prevalence of dementia, Alzheimer's disease (AD), and vascular dementia (VaD) among elderly Chinese individuals and to analyze differences between urban and rural areas. Methods: For the years 2008 to 2009, we performed a population-based cross-sectional survey with a multistage cluster sampling design. Residents aged 65 years and older were drawn from 30 urban (n = 6096) and 45 rural (n = 4180) communities across China. Participants were assessed with a series of clinical examinations and neuropsychological measures. Dementia, AD, and VaD were diagnosed according to established criteria via standard diagnostic procedures. Results: The prevalence of dementia, AD, and VaD among individuals aged 65 years and older were 5.14% (95% CI, 4.71-5.57), 3.21% (95% CI, 2.87-3.55), and 1.50% (95% CI, 1.26-1.74), respectively. The prevalence of dementia was significantly higher in rural areas than in urban ones (6.05% vs. 4.40%, P < .001). The same regional difference was also seen for AD (4.25% vs. 2.44%, P < .001) but not for VaD (1.28% vs. 1.61%, P = .166). The difference in AD was not evident when the sample was stratified by educational level. Moreover, the risk factors for AD and VaD differed for urban and rural populations. Conclusions: A notably higher prevalence of dementia and AD was found in rural areas than in urban ones, and education might be an important reason for the urban rural differences. (C) 2014 The Alzheimer's Association. All rights reserved.
基金：
National Key Technology R&D Program in the Eleventh Five-Year Plan Period(2006BAI02B01)
the National Natural Science Key Foundation of China (30830045)
the National Basic Research 973 Program (2006CB500700)
Beijing Natural Science Key Foundation (7071004)
第一作者机构：[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, P. R. China
通讯作者：
通讯机构：[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, P. R. China
推荐引用方式(GB/T 7714)：
Jianping Jia,Fen Wang,Cuibai Wei,et al.The prevalence of dementia in urban and rural areas of China[J].ALZHEIMERS & DEMENTIA.2014,10(1):1-9.doi:10.1016/j.jalz.2013.01.012.
APA：
Jianping Jia,Fen Wang,Cuibai Wei,Aihong Zhou,Xiangfei Jia...&Xiumin Dong.(2014).The prevalence of dementia in urban and rural areas of China.ALZHEIMERS & DEMENTIA,10,(1)
MLA：
Jianping Jia,et al."The prevalence of dementia in urban and rural areas of China".ALZHEIMERS & DEMENTIA 10..1(2014):1-9
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