机构：[1]Department of Vascular Surgery, XuanWu Hospital, and Institute of Vascular Surgery, Capital Medical University, Beijing, China.血管外科首都医科大学宣武医院[2]National Stroke Screening and Intervention Base[3]Beijing Center for Cerebrovascular Diseases, Beijing, China.
Purpose: To evaluate the immediate and long-term outcomes of drug-eluting stent (DES) vs. bare metal stent (BMS) for symptomatic vertebral artery stenosis (VAS). Methods: From 2003 to 2010, 206 consecutive patients (158 men; mean age 66.8 years) underwent DES (sirolimus-eluting or paclitaxel-eluting) or BMS placement for symptomatic extracranial and intracranial stenoses in 219 vertebral arteries. The technical success, clinical success, periprocedural complications, target vessel revascularization (TVR), and overall survival were compared between the DES and BMS groups. Results: The technical success rate was 98.3% (119/121) for the DES group vs. 100% for the BMS group (p=0.503). The clinical success rate was 95.5% (107/112) for the DES group vs. 97.9% (92/94) for the BMS group (p=0.592). No periprocedural death or stroke occurred. The overall periprocedural complication rate was 2.7% (3/112) in the DES group vs. 4.3% (4/94) in BMS group (p=0.813). The median follow-up was 43 months (range 3-95) for the DES group and 46 months (range 6-89) for BMS. At last follow-up, the TVR rate was 6.3% (7/112) for the DES group vs. 20.2% (19/94) for the BMS group (p=0.003); 4 (3.6%) patients in the DES group and 8 (8.5%) patients in the BMS group experienced a VBS stroke (p=0.132). By life-table analysis, the 5-year TVR rate was 4.5% (5/112) for the DES group vs. 19.1% (18/94) for the BMS group (p=0.001). No difference was detected in the overall survival curves between the groups (p=0.500). Conclusion: Both DES and BMS are feasible, safe, and effective for symptomatic VAS. However, DES can significantly decrease the TVR rate in the long term compared with BMS. J Endovasc Ther. 2012;19:231-238
第一作者机构：[1]Department of Vascular Surgery, XuanWu Hospital, and Institute of Vascular Surgery, Capital Medical University, Beijing, China.[2]National Stroke Screening and Intervention Base
通讯作者：
通讯机构：[*1]Department of Vascular Surgery, XuanWu Hospital, and Institute of Vascular Surgery, Capital Medical University, Changchun Street No 45, Beijing 100053, China.
推荐引用方式(GB/T 7714)：
Lipo Song,Jianxin Li,Yongquan Gu,et al.Drug-Eluting vs. Bare Metal Stents for Symptomatic Vertebral Artery Stenosis[J].JOURNAL OF ENDOVASCULAR THERAPY.2012,19(2):231-238.doi:10.1583/11-3718.1.
APA：
Lipo Song,Jianxin Li,Yongquan Gu,Hengxi Yu,Bing Chen...&Jian Zhang.(2012).Drug-Eluting vs. Bare Metal Stents for Symptomatic Vertebral Artery Stenosis.JOURNAL OF ENDOVASCULAR THERAPY,19,(2)
MLA：
Lipo Song,et al."Drug-Eluting vs. Bare Metal Stents for Symptomatic Vertebral Artery Stenosis".JOURNAL OF ENDOVASCULAR THERAPY 19..2(2012):231-238
