机构:[a]Beijing Comprehensive Epilepsy Diagnosis and Treatment Center, Beijing Institute of Functional Neurosurgery, Department of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, China神经外科首都医科大学宣武医院[b]Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, China神经内科首都医科大学宣武医院
Objective: The goal of this study was to summarize the results of language cortex mapping using electrical cortical stimulation with modified language tasks for Mandarin-speaking patients with epilepsy. Methods: Electrical currents were delivered through implanted subdural electrodes to six Mandarin-speaking patients before epilepsy surgery. The current intensities inducing any language disturbance during comprehension, repetition, and speech tasks were recorded, and individual cortical mapping was completed to guide subsequent resection, with the distance between mapped language sites and resected zones kept at a minimum of 0.5 cm. Language function was reassessed and followed up after surgery. Results: Language cortices were successfully identified in three patients, but demonstrated great variability in distribution. There seemed to be no difference in the intensity threshold that induced language interference. None of the six patients exhibited language deficits postsurgery. Conclusions: Electrical cortical stimulation with modified language tasks is valid for identification of cortices underlying Mandarin processing. The great variability in language cortex distribution enhances the necessity of individual language cortical mapping in epilepsy surgery. (C) 2010 Elsevier Inc. All rights reserved.
第一作者机构:[a]Beijing Comprehensive Epilepsy Diagnosis and Treatment Center, Beijing Institute of Functional Neurosurgery, Department of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, China[*]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, People's Republic of China
通讯作者:
通讯机构:[*]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, People's Republic of China
推荐引用方式(GB/T 7714):
Liang Qiao,Tao Yu,Wei Sun,et al.Cortical language mapping using electrical cortical stimulation for Mandarin-speaking patients with epilepsy: A report of six case studies[J].EPILEPSY & BEHAVIOR.2010,19(3):343-347.doi:10.1016/j.yebeh.2010.07.017.
APA:
Liang Qiao,Tao Yu,Wei Sun,Duanyu Ni&Yongjie Li.(2010).Cortical language mapping using electrical cortical stimulation for Mandarin-speaking patients with epilepsy: A report of six case studies.EPILEPSY & BEHAVIOR,19,(3)
MLA:
Liang Qiao,et al."Cortical language mapping using electrical cortical stimulation for Mandarin-speaking patients with epilepsy: A report of six case studies".EPILEPSY & BEHAVIOR 19..3(2010):343-347