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Cortical language mapping using electrical cortical stimulation for Mandarin-speaking patients with epilepsy: A report of six case studies

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机构: [a]Beijing Comprehensive Epilepsy Diagnosis and Treatment Center, Beijing Institute of Functional Neurosurgery, Department of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, China [b]Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, China
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关键词: Electrical cortical stimulation Language Mandarin Epilepsy surgery

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Objective: The goal of this study was to summarize the results of language cortex mapping using electrical cortical stimulation with modified language tasks for Mandarin-speaking patients with epilepsy. Methods: Electrical currents were delivered through implanted subdural electrodes to six Mandarin-speaking patients before epilepsy surgery. The current intensities inducing any language disturbance during comprehension, repetition, and speech tasks were recorded, and individual cortical mapping was completed to guide subsequent resection, with the distance between mapped language sites and resected zones kept at a minimum of 0.5 cm. Language function was reassessed and followed up after surgery. Results: Language cortices were successfully identified in three patients, but demonstrated great variability in distribution. There seemed to be no difference in the intensity threshold that induced language interference. None of the six patients exhibited language deficits postsurgery. Conclusions: Electrical cortical stimulation with modified language tasks is valid for identification of cortices underlying Mandarin processing. The great variability in language cortex distribution enhances the necessity of individual language cortical mapping in epilepsy surgery. (C) 2010 Elsevier Inc. All rights reserved.

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出版当年[2009]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 4 区 行为科学 4 区 精神病学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 行为科学 3 区 精神病学 4 区 临床神经病学
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出版当年[2008]版:
Q2 CLINICAL NEUROLOGY Q3 PSYCHIATRY Q3 BEHAVIORAL SCIENCES
最新[2023]版:
Q2 PSYCHIATRY Q2 BEHAVIORAL SCIENCES Q3 CLINICAL NEUROLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2008版] 出版当年五年平均 出版前一年[2007版] 出版后一年[2009版]

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第一作者机构: [a]Beijing Comprehensive Epilepsy Diagnosis and Treatment Center, Beijing Institute of Functional Neurosurgery, Department of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, China [*]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, People's Republic of China
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通讯机构: [*]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, People's Republic of China
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