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The multi-center study on Alzheimer's disease using FDG PET

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机构: [1]Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China [2]PET Center of Xuanwu Hospital, Capital University of Medical Sciences, Beijing, China [3]Shanghai mental health center, shanghai, China [4]Department of Nuclear Medicine, the Chinese PLA General Hospital, Beijing, China
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关键词: Alzheimer disease PET multicenter study glucose metabolism

摘要:
The multi-center FDG PET data of normal controls and patients with probable Alzheimer's disease (AD) were analyzed using SPM (statistical parametric mapping). The results have shown that the hypo-metabolic cerebral areas of patients with probable AD, comparing with health controls, were very consistent in the results of four group data from three PET centers. The significant hypo-metabolic areas located at the posterior cingulate, the joint area of temporal, parietal and occipital cortex, the inferior temporal gyrus and prefrontal cortex. The results of this multi-center study indicated that FDG PET scans might provide a reliable reference marker for AD diagnosis.

基金:

基金编号: 90209030

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第一作者机构: [1]Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China
通讯作者:
通讯机构: [1]Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China
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