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Efficacy of stenting in patients with cerebral venous sinus thrombosis-related cerebral venous sinus stenosis

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机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Department of Interventional Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China [3]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [4]Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, USA
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关键词: stenosis stent vein

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Background Venous stenting has been proven to be a safe and effective therapeutic option for patients with idiopathic intracranial hypertension (IIH) and cerebral venous sinus stenosis (CVSS). However, its use in patients with cerebral venous sinus thrombosis-related CVSS has been less reported. Purpose To explore the safety and efficacy of stenting for patients with cerebral venous sinus thrombosis (CVST)-related CVSS. Methods The clinical presentation, treatment, and outcome of patients with CVST-related CVSS received venous stenting in the chronic stage after failed medical treatment were retrospectively evaluated. Results A total of 17 patients with CVST-related CVSS were included. Mean pressure gradient across the CVSS decreased from 11.5±4.2 mmHg prior to stenting to 2.1±1.1 mmHg post-stenting. Mean CSF opening pressure decreased from 33.1±5.5 cmH 2 O to 18.7±1.7 cmH 2 O. Both headache and visual disturbance improved or resolved in 78% and 92% of the patients, respectively. Complications included lethal cerebellar hematoma in one case and bilateral occipital epidural hematoma in another case. One of the patients received retreatment with ventriculo-peritoneal shunting due to recurrent headache. Conclusion Restoring the patency of stenotic sinuses with stents in patients of CVST-related CVSS unresponsive to medical therapy in the chronic stage may improve symptoms in the majority of the patients. However, a relatively higher cerebral hemorrhage rate was observed and may be related to this pathology. Stenting in this subgroup of CVSS patients may require further evaluation with a larger and long-Term study, and should be used with caution at this time. © Author(s) (or their employer(s)) 2019.

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出版当年[2018]版:
大类 | 3 区 医学
小类 | 2 区 外科 3 区 神经成像
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 神经成像 1 区 外科
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出版当年[2017]版:
Q1 SURGERY Q2 NEUROIMAGING
最新[2023]版:
Q1 NEUROIMAGING Q1 SURGERY

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

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第一作者机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Department of Interventional Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China
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通讯机构: [*1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
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