Infected pancreatic necrosis(IPN) is one of the complications of acute pancreatitis(AP).Since it brings high mortality and heavy financial burden,more and more scholars begin to focus on its mechanism and treatment.This paper reviewed the research progress of the disease,from pathological,pathophysiologic and immunologic researches based on the animal and clinical experiments,to the actuality of diagnosis and treatment based on the practical work as well as international and domestic consensus.