机构：[1]Department of Cardiology, Capital Medical University, Beijing AnZhen Hospital, Beijing, China,临床科室心脏内科中心首都医科大学附属安贞医院[2]Department of Cardiology, Beijing Changping Hospital, Beijing, China,[3]Department of Vascular Surgery, Chinese PLA General Hospital, Beijing, China,[4]Vascular Surgery Research Laboratories, Division of Vascular and Endovascular Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA,[5]Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,医技科室医学影像科首都医科大学附属安贞医院[6]State Key Lab of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, China航天员中心
Myocardial fibrosis is an important part of cardiac remodeling that leads to heart failure and death. Myocardial fibrosis results from increased myofibroblast activity and excessive extracellular matrix deposition. Various cells and molecules are involved in this process, providing targets for potential drug therapies. Currently, the main detection methods of myocardial fibrosis rely on serum markers, cardiac magnetic resonance imaging, and endomyocardial biopsy. This review summarizes our current knowledge regarding the pathophysiology, quantitative assessment, and novel therapeutic strategies of myocardial fibrosis.
基金：
China Natural Science Funding [81101173, 81470429]; High Levels of Health Technical Personnel in Beijing City Health System [2013-3-005]
第一作者机构：[1]Department of Cardiology, Capital Medical University, Beijing AnZhen Hospital, Beijing, China,
通讯作者：
通讯机构：[1]Department of Cardiology, Capital Medical University, Beijing AnZhen Hospital, Beijing, China,
推荐引用方式(GB/T 7714)：
Tong Liu,Deli Song,Jianzeng Dong,et al.Current Understanding of the Pathophysiology of Myocardial Fibrosis and Its Quantitative Assessment in Heart Failure[J].FRONTIERS IN PHYSIOLOGY.2017,8(APR):-.doi:10.3389/fphys.2017.00238.
APA：
Tong Liu,Deli Song,Jianzeng Dong,Pinghui Zhu,Jie Liu...&Shukuan Ling.(2017).Current Understanding of the Pathophysiology of Myocardial Fibrosis and Its Quantitative Assessment in Heart Failure.FRONTIERS IN PHYSIOLOGY,8,(APR)
MLA：
Tong Liu,et al."Current Understanding of the Pathophysiology of Myocardial Fibrosis and Its Quantitative Assessment in Heart Failure".FRONTIERS IN PHYSIOLOGY 8..APR(2017):-
