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The Prevalence of Osteoporosis in China, a Nationwide, Multicenter DXA Survey

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机构： [1]Health Management Institute, Chinese PLA General Hospital, Beijing, China [2]Department of Radiology, Beijing Jishuitan Hospital, Beijing, China [3]Department of Statistic, Beijing Jishuitan Hospital, Beijing, China [4]Health Management Center, Weifang People’s Hospital, Weifang, Shandong Province, China [5]Health Check Center, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, Liaoning Province, China [6]Department of Endocrinology, The First Affiliated Hospital of Medical University of Anhui, Hefei, Anhui Province, China [7]Department of Nuclear Medicine, Sichuan Provincial People’s Hospital, Chengdu, Sichuan Province, China [8]Department of Nuclear Medicine, Beijing Hospital of Traditional Chinese Medicine, Beijing, China [9]Health Check Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China [10]Department of Osteopathic Internal Medicine, The 8th Medical Center of Chinese General Hospital, Beijing, China [11]Orthopedics department, The 8th Medical Center of Chinese General Hospital, Beijing, China [12]Editor Office of Chinese Health Management Journal, Beijing, China [13]Healthcare Department, Agency for Offices Administration of PLA, Beijing, China

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关键词： BONE MINERAL DENSITY CHINA DUAL-ENERGY X-RAY ABSORPTIOMETRY FEMORAL NECK LUMBAR SPINE OSTEOPOROSIS TOTAL FEMUR

摘要：

A number of studies investigated the distribution of BMD values and the prevalence of osteoporosis in China, but their findings varied. Until now, a BMD reference database based on uniform measurements in a large-scale Chinese population has been lacking. A total of 75,321 Chinese adults aged 20 years and older were recruited from seven centers between 2008 and 2018. BMD values at the lumbar spine (L1–L4), femoral neck, and total femur were measured by GE Lunar dual-energy X-ray absorptiometry systems. BMD values measured in each center were cross-calibrated by regression equations that were generated by scanning the same European spine phantom 10 times at every center. Cubic and multivariate linear regression were performed to assess associations between BMD values and demographic variables. Sex-specific prevalence of osteoporosis was age-standardized based on the year 2010 national census data for the Chinese population. The sex-specific BMD values at each site were negatively associated with age, positively associated with body mass index levels, and lower in the participants from southwest China than in those from other geographic regions after multivariate adjustment. Furthermore, BMD values at the femoral neck and total femur decreased with the year of BMD measurement. The peak BMD values at the lumbar spine, femoral neck, and total femur were 1.088 g/cm2, 0.966 g/cm2, and 0.973 g/cm2, respectively, for men, and 1.114 g/cm2, 0.843 g/cm2, and 0.884 g/cm2, respectively, for women. The age-standardized prevalence of osteoporosis at the spine or hip was 6.46% and 29.13% for men and women aged 50 years and older, respectively. Currently a total of 10.9 million men and 49.3 million women in China are estimated to have osteoporosis. In our national examination of BMD, we found that BMD values differed by demographic characteristics. We estimated the age-standardize prevalence of osteoporosis in China to be 6.46% and 29.13% respectively, for men and women aged 50 years and older. © 2019 American Society for Bone and Mineral Research

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出版当年[2018]版：

大类 | 2 区医学

小类 | 2 区内分泌学与代谢

最新[2023]版：

大类 | 1 区

医学

小类 | 1 区内分泌学与代谢

JCR分区：

出版当年[2017]版：

Q1 ENDOCRINOLOGY & METABOLISM

最新[2023]版：

Q1 ENDOCRINOLOGY & METABOLISM

影响因子： 5.1 最新[2023版] 5.8 最新五年平均 6.314 出版当年[2017版] 6.766 出版当年五年平均 6.284 出版前一年[2016版] 5.711 出版后一年[2018版]

第一作者：

第一作者机构： [1]Health Management Institute, Chinese PLA General Hospital, Beijing, China

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通讯作者：

通讯机构： [2]Department of Radiology, Beijing Jishuitan Hospital, Beijing, China [13]Healthcare Department, Agency for Offices Administration of PLA, Beijing, China [*1]Department of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.

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The Prevalence of Osteoporosis in China, a Nationwide, Multicenter DXA Survey