机构：[1]Department of Dermatology, Beijing Children’s Hospital, National Center for Children’s Health, Capital Medical University, Beijing, China临床科室职能科室临床流行病与循证医学中心皮肤科首都医科大学附属北京儿童医院[2]Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China[3]Department of Dermatology, Children’s Hospital of Chongqing Medical University, Chongqing, China[4]Department of Dermatology, Shenzhen Children’s Hospital, Shenzhen, China[5]Department of Dermatology, Harbin Children’s Hospital, Harbin, China[6]Department of Dermatology, Dalian Children’s Hospital of Dalian Medical University, Dalian, China
BackgroundTherapeutic patient education is a continuous, systematic, patient-centered learning process to help patients and their families acquire and maintain the skills they need to manage their lives with a chronic disease. It has been proven effective in increasing treatment adherence and improving quality of life for patients with atopic dermatitis (AD) in Western countries. We introduce the first multicenter, randomized controlled clinical trial of therapeutic patient education in Chinese children with AD. ObjectivesTo evaluate the effects of therapeutic patient education on the severity of AD, quality of life, and understanding and successful use of emollients in Chinese children with eczema. MethodsWe recruited 580 children, ages 2-14 years, with moderate to severe AD from six hospitals in China. Participants were randomized (1:1) to an intervention (n = 293) or control (n = 249) group. In addition to the severity of AD, data on quality of life and a questionnaire on family and patient knowledge of emollients were evaluated at the 6-month follow-up. ResultsOn study completion, we found that the intervention group showed a significantly greater reduction in mean SCORing Atopic Dermatitis (P < .001) and Infant's Dermatology Life Quality Index (P = .030) scores than the control group. In addition, knowledge about the use of emollients improved significantly in the intervention group. There was no significant difference between groups in Children's Dermatology Life Quality Index scores. ConclusionsThe first randomized controlled trial of a therapeutic patient education program in China had positive long-term effects on decreasing eczema severity and improvement of quality of life in children 2-4 years of age with AD, as well as in promoting greater understanding of the use of emollients.
基金：
Foundation for Atopic Dermatitis, Pierre Fabre Laboratory
第一作者机构：[1]Department of Dermatology, Beijing Children’s Hospital, National Center for Children’s Health, Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Dermatology, Beijing Children’s Hospital, National Center for Children’s Health, Capital Medical University, Beijing, China[*1]Department of Dermatology, Beijing Children’s Hospital, National Center for Children’s Health, Capital Medical University, Beijing, China.
推荐引用方式(GB/T 7714)：
Liang Yuan,Tian Jing,Shen Chun Ping,et al.Therapeutic patient education in children with moderate to severe atopic dermatitis: A multicenter randomized controlled trial in China[J].PEDIATRIC DERMATOLOGY.2018,35(1):70-75.doi:10.1111/pde.13362.
APA：
Liang, Yuan,Tian, Jing,Shen, Chun Ping,Xu, Feng,Wang, Hua...&Ma, Lin.(2018).Therapeutic patient education in children with moderate to severe atopic dermatitis: A multicenter randomized controlled trial in China.PEDIATRIC DERMATOLOGY,35,(1)
MLA：
Liang, Yuan,et al."Therapeutic patient education in children with moderate to severe atopic dermatitis: A multicenter randomized controlled trial in China".PEDIATRIC DERMATOLOGY 35..1(2018):70-75
