机构:[1]Department of Urology, Beijing Children’s Hospital Affiliated to Capital Medical University, No. 56 Nanlishi Road, Xicheng District, Beijing 100045, China临床科室泌尿外科首都医科大学附属北京儿童医院
We review our experience in urethrocutaneous fistula (UCF) repair after transverse preputial island flap urethroplasty (Duckett) in pediatric hypospadias to investigate the risk factors for unsuccessful outcome. Two hundred and nineteen UCFs repairs conducted in our center from January 2015 to December 2016 after Duckett technique were retrospectively reviewed and 182 had a follow-up for more than 6 months. The age of patients, size, localization and numbers of UCFs, interval time of two operations, length of neourethra, times of UCFs repairs, complications other than UCFs, hospital of primary surgery and postoperative infection were analyzed as potential risk factors. Stratified analysis and assessment of additive interaction were performed to have a better understanding of the relation between the risk factors. Logistic regression analysis was used for multivariate analysis. UCF repairs were succeeded in 121 (66.5%) and failed in 61 (33.5%) at first operation. In the univariate analysis, size and numbers of UCFs (P = 0.01 and P = 0.035, respectively), interval time of two operations (P = 0.042) and hospital of primary surgery (P = 0.02) were statistically related with the outcome. In the multivariate analysis, UCF ae<yen> 2 (OR 2.71, 95%, CI 1.095-6.692, P = 0.031), size ae<yen> 2 mm (OR 2.45, 95% CI 1.267-4.757, P = 0.08) and primary surgery not at our hospital (OR 2.21, 95% CI 1.094-4.126, P = 0.026) were identified as independent risk factors for unsuccessful outcome. In the stratified analysis, multiplicative interaction between the 3 risk factors was not found. Our study suggested that UCF repairs after transverse preputial island flap urethroplasty were easier to fail if the UCF was ae<yen> 2 mm, the numbers of UCFs was ae<yen> 2, or the surgeon had less experience. The age of patients, site of UCFs, interval time of two operations, length of neourethra, times of UCFs repairs, complications other than UCF and postoperative infection were not significantly related to the success rate of UCF repair.
基金:
Beijing outstanding talent training scheme [2016000021469G200]; Beijing hospital authority key medical professional development plan "yangfan" [ZYLX201709]; Beijing hospital authority "dengfeng" talent training plan [DFL20151102]
第一作者机构:[1]Department of Urology, Beijing Children’s Hospital Affiliated to Capital Medical University, No. 56 Nanlishi Road, Xicheng District, Beijing 100045, China
通讯作者:
通讯机构:[1]Department of Urology, Beijing Children’s Hospital Affiliated to Capital Medical University, No. 56 Nanlishi Road, Xicheng District, Beijing 100045, China
推荐引用方式(GB/T 7714):
Han Wenwen,Zhang Weiping,Sun Ning.f Risk factors for failed urethrocutaneous fistula repair after transverse preputial island flap urethroplasty in pediatric hypospadias[J].INTERNATIONAL UROLOGY AND NEPHROLOGY.2018,50(2):191-195.doi:10.1007/s11255-017-1773-x.
APA:
Han, Wenwen,Zhang, Weiping&Sun, Ning.(2018).f Risk factors for failed urethrocutaneous fistula repair after transverse preputial island flap urethroplasty in pediatric hypospadias.INTERNATIONAL UROLOGY AND NEPHROLOGY,50,(2)
MLA:
Han, Wenwen,et al."f Risk factors for failed urethrocutaneous fistula repair after transverse preputial island flap urethroplasty in pediatric hypospadias".INTERNATIONAL UROLOGY AND NEPHROLOGY 50..2(2018):191-195