机构：[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China重点科室诊疗科室神经病学中心神经病学中心首都医科大学附属天坛医院[2]Department of Respiratory, Kailuan Hospital, North China University of Science and Technology, Tangshan, China[3]Department of General Practice Medical, Kailuan General Hospital, Tangshan, China[4]Department of Neurology, Kailuan General Hospital, Tangshan, China[5]Department of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China[6]Department of Internal Medcine, Maternal and Child Health Hospital of Tangshan, Tangshan, China[7]Department of Intensive Care Unit, Kailuan Hospital, North China University of Science and Technology, Tangshan, China[8]China National Clinical Research Center for Neurological Diseases, Beijing, China[9]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China[10]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
The association between blood pressure variability (BPV) and the risk of all-cause mortality and cardiovascular diseases (CVD) is not well understood. The Kailuan study is a prospective longitudinal cohort study on cerebrovascular events and cardiovascular factors. In this study, resting blood pressure was measured at baseline and every 2years from 2006 to 2007. BPV is mainly defined as the coefficient of variation (CV). Hazard ratio (HR), with 95% confidence intervals (CI) was calculated using Cox regression model. Among 52387 participants, we identified 1817 who ended up with all-cause death and 1198 with CVD. Each 4.68% increase in BPV was associated with a 13% increase in the risk of mortality (HR=1.13, 95% CI=1.09-1.18) and a 7% increase in CVD (HR=1.07, 95% CI=1.02-1.13), respectively. After adjustment of confounding factors, the HR of comparing participants in the highest versus lowest quartile of CV of systolic blood pressure (SBP) was 1.37 (1.19, 1.57) for all-cause death, 1.18 (1.01, 1.39) for CVD. Similar results were also observed when BPV was measured by different parameters. We concluded that visit-to-visit BPV was associated with all-cause death and cardiovascular and cerebrovascular events in Chinese general population.
第一作者机构：[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China[5]Department of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China[8]China National Clinical Research Center for Neurological Diseases, Beijing, China[9]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China[10]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China[*1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.[*2]Department of General Practice Medical, Kailuan General Hospital, Tangshan, China.
推荐引用方式(GB/T 7714)：
Liye Dai,Lu Song,Xiaoli Li,et al.Association of visit-to-visit blood pressure variability with the risk of all-cause mortality and cardiovascular events in general population[J].JOURNAL OF CLINICAL HYPERTENSION.2018,20(2):280-288.doi:10.1111/jch.13192.
APA：
Liye Dai,Lu Song,Xiaoli Li,Yuling Yang,Xiaoming Zheng...&Yongjun Wang.(2018).Association of visit-to-visit blood pressure variability with the risk of all-cause mortality and cardiovascular events in general population.JOURNAL OF CLINICAL HYPERTENSION,20,(2)
MLA：
Liye Dai,et al."Association of visit-to-visit blood pressure variability with the risk of all-cause mortality and cardiovascular events in general population".JOURNAL OF CLINICAL HYPERTENSION 20..2(2018):280-288
