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Meningococcal disease and control in China: Findings and updates from the Global Meningococcal Initiative (GMI)

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机构: [1]National Immunisation Programme Department, Chinese Center for Disease Control and Prevention, Beijing, China [2]State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China [3]Department of Infectious Disease, Beijing Children’s Hospital, Beijing, China [4]Meningococcal Reference Unit, Public Health England, Manchester Royal Infirmary, Manchester, UK [5]Department of Microbiology, Center for Disease Control and Prevention, Shanghai, China [6]Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China [7]Department of Immunology, Center for Disease Control and Prevention, Liaoning, China [8]National Reference Centre for Meningococci, Institute Pasteur, Paris, France [9]Department of Infectious Diseases, the First Affiliated Hospital of Anhui Medical University, China [10]Department of Immunization Programme, Center for Disease Control and Prevention, Guangdong, China
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关键词: Meningococcal disease China Vaccination Polysaccharide vaccine Conjugate vaccine Surveillance Epidemiology Immunization program Neisseria meningitidis Bacterial meningitis

摘要:
The Global Meningococcal Initiative (GMI) is a global expert group, including scientists, clinicians and public health officials from a wide range of specialities. The goal of the GMI is to prevent meningococcal disease worldwide through education, research, and co-operation. The Chinese GMI roundtable meeting was held in June 2017. The GMI met with local experts to gain insight into the meningococcal disease burden in China and current prevention and vaccination strategies in place. China experienced five epidemics of serogroup A meningococcal disease (MenA) between 1938 and 1977, with peak incidence of 403/100,000 recorded in 1967. MenA incidence rates have significantly declined following the universal introduction of the MenA polysaccharide vaccine in China in the 1980s. Further, surveillance data indicates changing meningococcal epidemiology in China with the emergence of new clones of serogroup B from serogroup C clonal complex (cc) 4821 due to capsular switching, and the international spread of serogroup W cc11. The importance of carriage and herd protection for controlling meningococcal disease was highlighted with the view to introduce conjugate vaccines and serogroup B vaccines into the national immunization schedule. Improved disease surveillance and standardized laboratory techniques across and within provinces will ensure optimal epidemiological monitoring. Crown Copyright (C) 2018 Published by Elsevier Ltd on behalf of The British Infection Association.

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出版当年[2017]版:
大类 | 2 区 医学
小类 | 2 区 传染病学
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 传染病学
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出版当年[2016]版:
Q1 INFECTIOUS DISEASES
最新[2023]版:
Q1 INFECTIOUS DISEASES

影响因子: 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

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第一作者机构: [1]National Immunisation Programme Department, Chinese Center for Disease Control and Prevention, Beijing, China
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通讯机构: [4]Meningococcal Reference Unit, Public Health England, Manchester Royal Infirmary, Manchester, UK [*1]Meningococcal Reference Unit, Public Health England, Manchester Royal Infirmary, Manchester, M13 9WZ, United Kingdom.
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