机构：[1]Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,重点科室诊疗科室神经病学中心神经病学中心首都医科大学附属天坛医院[2]Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,重点科室诊疗科室神经病学中心神经病学中心首都医科大学附属天坛医院[3]China National Clinical Research Center for Neurological Diseases, Beijing, China,[4]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[5]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China,[6]Department of Clinical Psychology, Capital Medical University, Beijing, China,[7]Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Taipa, Macau,[8]Department of Interventional Neuroradiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,重点科室医技科室放射科放射科首都医科大学附属天坛医院[9]University of Notre Dame Australia, Marian Centre and Graylands Hospital, Perth, WA, Australia,[10]Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia
Objective: Few studies have examined the association between post-stroke depression (PSD), aphasia, and physical independence in Chinese patients. This study investigated the above association in stroke patients in China at 3-month follow-up. Methods: Altogether 270 patients within 14 days after ischemic stroke were recruited and followed up at 3 months. PSD, aphasia, and physical functional status were measured using the Stroke Aphasia Depression Questionnaire (SADQ), Western Aphasia Battery (WAB), and modified Rankin Scale (mRS), respectively. Patients with mRS total score > 2 were considered as having "physical dependence." Results: Out of 248 patients at 3-month follow up, 119 (48%) were rated as having physical dependence. Multiple logistic regression analyses revealed that female (p = 0.04; OR = 2.2; 95% CI: 1.0-5.1), more severe stroke at admission (p < 0.01; OR = 1.4; 95% CI: 1.3-1.5), and more severe PSD at 3 months (p = 0.01; OR = 1.05; 95% CI: 1.01-1.1) were independently associated with physical dependence at 3 months. Conclusions: Greater PSD and stroke severity were independently associated with physical dependence at 3months after stroke. Aphasia was also associated with physical dependence but the relationship was not significant. Early and effective depression screening, treatment and stroke rehabilitation appear to be important to improve the physical outcome and reduce the burden of stroke survivors.
基金：
Ministry of Science and TechnologyMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT); Ministry of Health of the People's Republic of China; National Key Research & Development Program of China [2016YFC1301720]; Beijing Brain Research [Z161100000216131]; Beijing Municipal Science and Technology CommissionBeijing Municipal Science & Technology Commission [Z151100004015127]; Build High Level Technology Talents of Health System in Beijing [2015-3-038]
第一作者机构：[1]Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,[2]Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,[3]China National Clinical Research Center for Neurological Diseases, Beijing, China,[4]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[5]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China,
通讯作者：
通讯机构：[1]Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,[2]Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,[3]China National Clinical Research Center for Neurological Diseases, Beijing, China,[4]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[5]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China,[6]Department of Clinical Psychology, Capital Medical University, Beijing, China,
推荐引用方式(GB/T 7714)：
Wang Shuo,Wang Chun-Xue,Zhang Ning,et al.The Association Between Post-stroke Depression, Aphasia, and Physical Independence in Stroke Patients at 3-Month Follow-Up[J].FRONTIERS IN PSYCHIATRY.2018,9(AUG):-.doi:10.3389/fpsyt.2018.00374.
APA：
Wang, Shuo,Wang, Chun-Xue,Zhang, Ning,Xiang, Yu-Tao,Yang, Yang...&Ng, Chee H..(2018).The Association Between Post-stroke Depression, Aphasia, and Physical Independence in Stroke Patients at 3-Month Follow-Up.FRONTIERS IN PSYCHIATRY,9,(AUG)
MLA：
Wang, Shuo,et al."The Association Between Post-stroke Depression, Aphasia, and Physical Independence in Stroke Patients at 3-Month Follow-Up".FRONTIERS IN PSYCHIATRY 9..AUG(2018):-
