Effects of ambient carbon monoxide on daily hospitalizations for cardiovascular disease: a time-stratified case-crossover study of 460,938 cases in Beijing, China from 2013 to 2017
机构：[1]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing, China.[3]Department of Epidemiology and Biostatistics, College of Public Health, Temple University, Philadelphia, USA.[4]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.重点科室诊疗科室神经外科神经外科首都医科大学附属天坛医院[5]Department of Mathematics and Statistics, La Trobe University, Melbourne, VIC, Australia.[6]School of Mathematical Sciences and Center for Statistical Science, Peking University, Beijing, China.[7]Beijing Municipal Commission of Health and Family Planning Information Center, Beijing, China.[8]Global Health and Genomics, School of Medical Sciences and Health, Edith Cowan University, Perth, WA, Australia.[9]Guanghua Group Pty Ltd, Melbourne, VIC, Australia.[10]Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
BackgroundEvidence focused on exposure to ambient carbon monoxide (CO) and the risk of hospitalizations for cardiovascular diseases (CVD) is lacking in developing countries. This study aimed to examine the effect of CO exposure on hospitalizations for CVD in Beijing, China.MethodsA total of 460,938 hospitalizations for cardiovascular diseases were obtained from electronic hospitalization summary reports from 2013 to 2017. A time-stratified case-crossover design was conducted to investigate the association between CO exposure and hospitalizations for total and cause-specific CVD, including coronary heart disease (CHD), atrial fibrillation (AF), and heart failure (HF). Stratified analysis was also conducted by age group (18-64years and65years) and sex.ResultsLinear exposure-response curves for the association between ambient CO exposure and hospitalizations for CVD was observed. Ambient CO was positively associated with hospitalizations for total CVD and CHD. However, the observed increased risk was not statistically significant for hospitalizations for AF and HF. The strongest effect of CO concentration was observed on the current- and previous-day of exposure (lag (0-1) day). For a 1mg/m(3) increase in a 2-day moving average CO concentration, an increase of 2.8% [95% confidence interval (CI): 2.2 to 3.3%] and 3.0% (95% CI: 2.4 to 3.6%) in daily hospital admissions for CVD and CHD were estimated, respectively. This association was robust after adjusting for other copollutants and did not vary by age group and sex.ConclusionsAmbient CO exposure increased the risk of hospitalizations for CVD, especially for CHD in Beijing. Further studies are warranted to explore the association between ambient CO and hospitalizations for AF and HF.
基金：
Program of Natural Science Fund of ChinaNational Natural Science Foundation of China [81773512]; National Key Basic Research Project of ChinaNational Basic Research Program of China [2016YFC0207705]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|2 区环境科学与生态学
小类|2 区环境科学2 区公共卫生、环境卫生与职业卫生
最新[2025]版：
大类|2 区环境科学与生态学
小类|1 区公共卫生、环境卫生与职业卫生2 区环境科学
JCR分区：
出版当年[2016]版：
Q1ENVIRONMENTAL SCIENCESQ1PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版：
Q1ENVIRONMENTAL SCIENCESQ1PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[1]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing, China.
通讯作者：
通讯机构：[1]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing, China.
推荐引用方式(GB/T 7714)：
Haibin Li,Jingwei Wu,Anxin Wang,et al.Effects of ambient carbon monoxide on daily hospitalizations for cardiovascular disease: a time-stratified case-crossover study of 460,938 cases in Beijing, China from 2013 to 2017[J].ENVIRONMENTAL HEALTH.2018,17(1):-.doi:10.1186/s12940-018-0429-3.
APA：
Haibin Li,Jingwei Wu,Anxin Wang,Xia Li,Songxi Chen...&Xiuhua Guo.(2018).Effects of ambient carbon monoxide on daily hospitalizations for cardiovascular disease: a time-stratified case-crossover study of 460,938 cases in Beijing, China from 2013 to 2017.ENVIRONMENTAL HEALTH,17,(1)
MLA：
Haibin Li,et al."Effects of ambient carbon monoxide on daily hospitalizations for cardiovascular disease: a time-stratified case-crossover study of 460,938 cases in Beijing, China from 2013 to 2017".ENVIRONMENTAL HEALTH 17..1(2018):-
