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Primary spinal primitive neuroectodermal tumor: A single center series with literature review

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机构： [1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing, People’s Republic of China, [2]National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders and Beijing Key Laboratory of Brain Tumor, Beijing, People’s Republic of China

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关键词： Extramedullary Intramedullary Primary Primitive neuroectodermal tumor (PNET) Spinal

摘要：

Context: Primary spinal primitive neuroectodermal tumor (PNET) of the central nervous system has a low incidence. The intraspinal case is very rare. Around 30 cases have been reported so far. We summarized the cases of primary spinal PNET available in the database of our institute, either intramedullary or extramedullary cases. Then we did literature review of the same disease. Findings: There were eight cases of primary spinal PNET available in our database, with one intramedullary case and seven extramedullary cases. Surgical resection was performed. The histology diagnosis was PNET. Peri-operative image examinations of the whole central nervous system (CNS) were performed to exclude tumors other than spinal cord origin. Then during literature review, 33 reports of the disease were included. The pre-operative diagnosis rate was low. The disease had a high recurrence rate and poor prognosis given available treatment. Conclusion: Primary spinal primitive neuroectodermal tumor is of high malignancy. Little is known due to its quite low incidence. The prognosis is poor due to lacking of effective treatment strategy. Present treatment strategy is referred to other common CNS malignancies like glioma. Further investigation of the disease is necessary. © 2018, © The Academy of Spinal Cord Injury Professionals, Inc. 2018.

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出版当年[2017]版：

大类 | 4 区医学

小类 | 4 区临床神经病学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学

第一作者：

第一作者机构： [1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing, People’s Republic of China, [2]National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders and Beijing Key Laboratory of Brain Tumor, Beijing, People’s Republic of China

通讯作者：

通讯机构： [1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing, People’s Republic of China, [2]National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders and Beijing Key Laboratory of Brain Tumor, Beijing, People’s Republic of China [*1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Dongcheng District Tiantanxili No. 6, Beijing, People’s Republic of China

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