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Glioma in Patients with Autosomal-Dominant Polycystic Kidney Disease

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收录情况： ◇ SCIE

作者：

机构： [1]Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R China; [2]Capital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China; [3]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [4]NCI, Neurooncol Branch, Bethesda, MD 20892 USA

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关键词： Autosomal-dominant polycystic kidney disease Glioma Treatment

摘要：

BACKGROUND: Autosomal-dominant polycystic kidney disease (ADPKD) is an inherited systemic condition with a predominant feature of cyst formation in both kidneys. An association with intracranial glioma has not been described previously in ADPKD. CASE DESCRIPTION: We report 2 cases of glioma in patients with ADPKD. One patient had a cystic lesion with contrast enhancement in the right temporal lobe as revealed by magnetic resonance imaging and an aneurysm in left sylvian fissure confirmed by computed tomography angiography. Subsequent histopathologic analysis of the resected enhancing lesion confirmed the diagnosis of glioblastoma (World Health Organization grade IV). The second patient was found to harbor a solid lesion in the right parietal lobe. This lesion also proved to be an astrocytoma (World Health Organization grade II). CONCLUSIONS: These 2 independent cases of glioma suggest an unusual clinical manifestation of ADPKD. The potential association between ADPKD and glioma pathogenesis should be further explored.

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出版当年[2016]版：

大类 | 3 区医学

小类 | 3 区临床神经病学 3 区外科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区外科

JCR分区：

出版当年[2015]版：

Q1 SURGERY Q2 CLINICAL NEUROLOGY

最新[2023]版：

Q2 SURGERY Q3 CLINICAL NEUROLOGY

影响因子： 1.9 最新[2023版] 2 最新五年平均 2.685 出版当年[2015版] 2.59 出版当年五年平均 2.878 出版前一年[2014版] 2.592 出版后一年[2016版]

第一作者：

第一作者机构： [1]Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R China; [3]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [4]NCI, Neurooncol Branch, Bethesda, MD 20892 USA

通讯作者：

通讯机构： [1]Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R China; [3]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China;

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