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Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay

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收录情况: ◇ SCIE

机构: [1]Capital Med Univ, Natl TB Clin Lab, Beijing Key Lab Drug Resistance TB Res, Beijing TB & Thorac Tumor Res Ins,Beijing Chest, 97 Machang, Beijing 101149, Peoples R China; [2]Capital Med Univ, Beijing Key Lab Pediat Dis Otolaryngol Head & Nec, Beijing Pediat Res Inst, Beijing Childrens Hosp, Beijing, Peoples R China; [3]Guangzhou Chest Hosp, Dept Clin Lab, State Key Lab Resp Dis, Guangzhou, Guangdong, Peoples R China; [4]Chinese Ctr Dis Control & Prevent, Natl Ctr TB Control & Prevent, 155 Chang Bai Rd, Beijing 102206, Peoples R China
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关键词: Mycobacterium tuberculosis GeneXpert Nontuberculous mycobacteria

摘要:
Out of 12 nontuberculous mycobacteria (NTM) species, 5 were identified as Mycobacterium tuberculosis (MTB) by GeneXpert at a bacterial load of 10(6). Notably, two species, including M. abscessus and M. smegmatis, were flagged as RIF-resistant MTB due to the high C(t) value of Probe E. In conclusion, our data have demonstrated that the misdiagnosis of MTB by GeneXpert assay is observed in five NTM species at a high bacterial load.

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出版当年[2016]版:
大类 | 3 区 医学
小类 | 3 区 传染病学
最新[2023]版:
大类 | 2 区 医学
小类 | 3 区 传染病学
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出版当年[2015]版:
Q3 INFECTIOUS DISEASES
最新[2023]版:
Q1 INFECTIOUS DISEASES

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

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第一作者机构: [1]Capital Med Univ, Natl TB Clin Lab, Beijing Key Lab Drug Resistance TB Res, Beijing TB & Thorac Tumor Res Ins,Beijing Chest, 97 Machang, Beijing 101149, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Natl TB Clin Lab, Beijing Key Lab Drug Resistance TB Res, Beijing TB & Thorac Tumor Res Ins,Beijing Chest, 97 Machang, Beijing 101149, Peoples R China; [4]Chinese Ctr Dis Control & Prevent, Natl Ctr TB Control & Prevent, 155 Chang Bai Rd, Beijing 102206, Peoples R China
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