机构：[1]Department of Respiratory Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of China临床科室职能科室呼吸科临床流行病与循证医学中心首都医科大学附属北京儿童医院[2]Department of Laboratory Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of China医技科室职能科室检验中心临床流行病与循证医学中心首都医科大学附属北京儿童医院[3]Department of Pediatrics, Maternal and Child Health Care Hospital of Shunyi District, Beijing, People’s Republic of China[4]Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China[5]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of China临床科室科研平台职能科室耳鼻咽喉头颈外科临床流行病与循证医学中心儿科研究所首都医科大学附属北京儿童医院
Mycobacterium abscessus complex (MABC) is an uncommon but increasingly important cause of invasive pulmonary disease, a condition associated with diagnostic and management challenges. MABC has mainly been reported in children with certain medical conditions, such as preexisting structural lung disorders and immunocompromised status. In this article, we describe a rare case of MABC pulmonary disease in an otherwise healthy infant. A 4-month-old female presented with cough and fever for 4 days. Computed tomography showed multiple masses and small nodules across both lungs. Isolated mycobacteria from her bronchoalveolar lavage fluid and gastric aspirate were identified as MABC by using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and M. abscessus subsp. massiliense was ultimately identified by DNA sequence analysis. Prolonged treatment with a combination of azithromycin, cefoxitin, and moxifloxacin achieved a successful treatment outcome.
基金：
Clinical Research Special Fund of Wu Jieping Medical Foundation [320.6750.160.56]
第一作者机构：[1]Department of Respiratory Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of China
通讯作者：
通讯机构：[1]Department of Respiratory Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of China[5]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of China[*1]Department of RespiratoryMedicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Nanlishi Road 56, Xicheng District, Beijing, People’s Republic of China[*2]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Nanlishi Road 56, Xicheng District, Beijing, People’s Republic of China
推荐引用方式(GB/T 7714)：
Liu Hui,Dong Fang,Liu Jinrong,et al.Successful management of Mycobacterium abscessus complex lung disease in an otherwise healthy infant[J].INFECTION AND DRUG RESISTANCE.2019,12:1277-1283.doi:10.2147/IDR.S198461.
APA：
Liu, Hui,Dong, Fang,Liu, Jinrong,Liu, Jianhua,Pang, Yu...&Li, Huimin.(2019).Successful management of Mycobacterium abscessus complex lung disease in an otherwise healthy infant.INFECTION AND DRUG RESISTANCE,12,
MLA：
Liu, Hui,et al."Successful management of Mycobacterium abscessus complex lung disease in an otherwise healthy infant".INFECTION AND DRUG RESISTANCE 12.(2019):1277-1283
