DNA self-assembly provides a powerful approach for preparation of nanostructures. It is often studied in bulk solution and involves only DNA-DNA interactions. When confined to surfaces, DNA-surface interactions become an additional, important factor to DNA self-assembly. However, the way in which DNA-surface interactions influence DNA self-assembly is not well studied. In this study, we showed that weak DNA-DNA interactions could be stabilized by DNA-surface interactions to allow large DNA nanostructures to form. In addition, the assembly can be conducted isothermally at room temperature in as little as 5 seconds.
基金:
Office of Naval ResearchOffice of Naval Research [N00014-15-1-2707]; National Science FoundationNational Science Foundation (NSF) [CMMI-1437301]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21605033]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [JZ2016HGPA0734]; China Scholarship CouncilChina Scholarship Council
第一作者机构:[1]Purdue Univ, Dept Chem, W Lafayette, IN 47906 USA;
通讯作者:
通讯机构:[1]Purdue Univ, Dept Chem, W Lafayette, IN 47906 USA;[4]Capital Med Univ, Beijing Tiantan Hosp, Dept Gen Surg, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Liu Longfei,Li Yulin,Wang Yong,et al.Regulating DNA Self-assembly by DNA-Surface Interactions[J].CHEMBIOCHEM.2017,18(24):2404-2407.doi:10.1002/cbic.201700545.
APA:
Liu, Longfei,Li, Yulin,Wang, Yong,Zheng, Jianwei&Mao, Chengde.(2017).Regulating DNA Self-assembly by DNA-Surface Interactions.CHEMBIOCHEM,18,(24)
MLA:
Liu, Longfei,et al."Regulating DNA Self-assembly by DNA-Surface Interactions".CHEMBIOCHEM 18..24(2017):2404-2407