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Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China

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机构： [a]Graduate School of Anhui Medical University, Hefei, 230032, China [b]State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China [c]Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing, 100191, China [d]Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, China [e]Department of Developmental Biology, Affiliated Bayi Children's Hospital, PLA Army General Hospital, Beijing, 100700, China [f]Department of Epidemiology, Tong Zhou Institute of Infectious Disease and Epidemiology, Beijing, 101113, China

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关键词： acute respiratory tract infection China epidemiology WU polyomavirus

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Aim: To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. Materials & methods: A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract infections. WUPyV was detected using real-time PCR and complete genome was sequenced for randomly selected positive nasopharyngeal aspirate. Results: Altogether 122 (7.5%) of 1617 children found to be infected with WUPyV and 88 (72.1%) were coinfected with other viruses during 2012-2015. The phylogenetic analysis showed that 14 strains from our study formed two new clusters (Id and IIIc) within the Branch I and Branch III, respectively. Conclusion: WUPyV is persistently circulating in China. Surveillance on WUPyV infection in wider areas and long persistence is warranted. © 2017 Future Medicine Ltd.

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出版当年[2016]版：

大类 | 2 区生物

小类 | 2 区微生物学

最新[2025]版：

大类 | 4 区生物学

小类 | 4 区微生物学

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