Reconstructive Endovascular Treatment of Spontaneous Symptomatic Large or Giant Vertebrobasilar Dissecting Aneurysms: Clinical and Angiographic Outcomes
To investigate the clinical and angiographic outcomes of spontaneous symptomatic large or giant vertebrobasilar dissecting aneurysms (VBDAs) following reconstructive endovascular treatment (EVT) with stent(s). We retrospectively identified 21 patients with spontaneous symptomatic large or giant VBDAs who had been treated with reconstructive EVT between September 2009 and September 2013 in our department. There were 20 men and 1 woman, with a mean age of 46.5 years (range: 17-67 years). Clinical and angiographic data were reviewed and evaluated. Reconstructive EVT with sole stenting (SS, 10 cases) or stent-assisted coiling (SAC, 11 cases) technique was technically feasible in all cases. Angiographic follow-up results confirmed delayed thrombosis of the aneurysm sac in only two of the eight cases after SS, and recurrence of the aneurysm sac in six of the nine cases after SAC. Postoperative complications or poor neurologic outcomes occurred in seven cases (33.3 %). Three patients died after SS, including postoperative subarachnoid hemorrhage in one case and pulmonary embolism in one case. The other patient died soon after SAC, without radiologic result to confirm the causes of death. Other adverse events after treatment include ischemic complication in two cases, intramural hemorrhage in one case, aggravation of initial mass effect in one case. As to the other 14 cases, the post-procedural processes were uneventful and no complication was observed. The condition of them was improved in seven cases (33.3 %), and unchanged in seven cases (33.3 %) during followAup. Reconstructive EVT with traditional intracranial stent(s) for the treatment of large and giant VBDAs carries a high failure rate and substantial risk of complications. The outcome of treating these difficult lesions with traditional intracranial stenting seems questionable and unpredictable.
基金:
National Science Foundation of ChinaNational Natural Science Foundation of China [81220108007, 81171079, 81371315, 81471167]; Special Research Project for Capital Health Development [2011-1015-04, 2014-1-1071]
语种:
外文
被引次数:
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PubmedID:
中科院(CAS)分区:
出版当年[2015]版:
大类|4 区医学
小类|3 区核医学4 区临床神经病学
最新[2023]版:
大类|3 区医学
小类|3 区临床神经病学3 区核医学
JCR分区:
出版当年[2014]版:
Q2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ3CLINICAL NEUROLOGY
最新[2023]版:
Q2CLINICAL NEUROLOGYQ2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
第一作者机构:[1]Capital Med Univ, Beijing Neurosurg Inst, 6 Tiantan Xili, Beijing 100050, Peoples R China;[2]Capital Med Univ, Beijing Tiantan Hosp, 6 Tiantan Xili, Beijing 100050, Peoples R China
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Neurosurg Inst, 6 Tiantan Xili, Beijing 100050, Peoples R China;[2]Capital Med Univ, Beijing Tiantan Hosp, 6 Tiantan Xili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Mu S.,Li C.,Yang X.,et al.Reconstructive Endovascular Treatment of Spontaneous Symptomatic Large or Giant Vertebrobasilar Dissecting Aneurysms: Clinical and Angiographic Outcomes[J].CLINICAL NEURORADIOLOGY.2016,26(3):291-300.doi:10.1007/s00062-014-0369-4.
APA:
Mu, S.,Li, C.,Yang, X.,Wang, Y.,Li, Y....&Wu, Z..(2016).Reconstructive Endovascular Treatment of Spontaneous Symptomatic Large or Giant Vertebrobasilar Dissecting Aneurysms: Clinical and Angiographic Outcomes.CLINICAL NEURORADIOLOGY,26,(3)
MLA:
Mu, S.,et al."Reconstructive Endovascular Treatment of Spontaneous Symptomatic Large or Giant Vertebrobasilar Dissecting Aneurysms: Clinical and Angiographic Outcomes".CLINICAL NEURORADIOLOGY 26..3(2016):291-300