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Screening for cognitive impairment with the Montreal Cognitive Assessment in Chinese patients with acute mild stroke and transient ischaemic attack: a validation study

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机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [2]Natl Univ Hlth Syst, Yong Loo Lin Sch Med, Dept Pharmacol, Singapore, Singapore; [3]Univ New South Wales, Sch Psychiat, Ctr Hlth Brain Ageing CHeBA, Sydney, NSW, Australia; [4]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [5]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Tiantan Clin Trial & Res Ctr Stroke, Beijing, Peoples R China; [6]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Vasc Neurol, Beijing, Peoples R China; [7]Prince Wales Hosp, Neuropsychiat Inst, Sydney, NSW, Australia; [8]Capital Med Univ, Beijing Tiantan Hosp, Dept Geriatr, Beijing, Peoples R China; [9]Beijing Inst Brain Disorders, Ctr Parkinson Dis, Beijing, Peoples R China; [10]Beijing Key Lab Parkinson Dis, Beijing, Peoples R China
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关键词: cognitive impairment mild stroke Montreal Cognitive Assessment-Beijing transient ischemic attack

摘要:
Objective: We aimed to establish the cut-off point of the Montreal Cognitive Assessment (MoCA-Beijing) in screening for cognitive impairment (CI) within 2 weeks of mild stroke or transient ischaemic attack (TIA). Methods: A total of 80 acute mild ischaemic stroke patients and 22 TIA patients were recruited. They received the MoCA-Beijing and a formal neuropsychological test battery. CI was defined by 1.5 SD below the established norms on a formal neuropsychological test battery. Results: Most stroke and TIA patients were in their 50s (53.95 +/- 11.43 years old), with greater than primary school level of education. The optimal cut-off point for MoCA-Beijing in discriminating patients with CI from those with no cognitive impairment (NCI) was 22/23 (sensitivity 85%, specificity 88%, positive predictive value=91%, negative predictive value=80%, classification accuracy=86%). The predominant cognitive deficits were characteristic of frontal-subcortical impairment, such as visuomotor speed (46.08%), attention/executive function (42.16%) and visuospatial ability (40.20%). Conclusions: A MoCA-Beijing cut-off score of 22/23 is optimally sensitive and specific for detecting CI after mild stroke, and TIA in the acute stroke phase, and is recommended for routine clinical practice.

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出版当年[2015]版:
大类 | 4 区 医学
小类 | 3 区 医学:内科
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
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出版当年[2014]版:
Q2 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q1 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

第一作者:
第一作者机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [4]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [5]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Tiantan Clin Trial & Res Ctr Stroke, Beijing, Peoples R China; [6]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Vasc Neurol, Beijing, Peoples R China;
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