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Rosai-Dorfman Disease of Rare Isolated Spinal Involvement: Report of 4 Cases and Literature Review

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收录情况： ◇ SCIE

作者：

机构： [1]Capital Med Univ, San Bo Brain Hosp, Dept Neurosurg, Beijing, Peoples R China; [2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R China; [3]Capital Med Univ, Coll Tradit Chinese Med, Beijing, Peoples R China

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关键词： Isolated spinal involvement Rosai-Dorfman disease

摘要：

BACKGROUND: Rosai-Dorfman disease (RDD) is a rare histioproliferative disorder that only occasionally involves the central nervous system (CNS). CASE DESCRIPTION: The diagnosis and treatment of 4 patients with isolated spinal RDD are discussed. All 4 patients were treated by total or subtotal surgical resection and none of them experienced recurrence. Histopathologic examination showed a characteristic emperipolesis, and the lymphocytes were engulfed in the S-100-protein-positive histiocytes with no expression of CD1a. CONCLUSIONS: Preoperative diagnosis of spinal RDD is still challenging because the lesion is usually a dura-based lesion that mimics a meningioma. Surgical resection is an effective treatment, and radiotherapy, steroid therapy, and chemotherapy have not shown reliable therapeutic efficiency.

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出版当年[2015]版：

大类 | 3 区医学

小类 | 3 区临床神经病学 3 区外科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区外科

JCR分区：

出版当年[2014]版：

Q1 SURGERY Q2 CLINICAL NEUROLOGY

最新[2023]版：

Q2 SURGERY Q3 CLINICAL NEUROLOGY

影响因子： 1.9 最新[2023版] 2 最新五年平均 2.878 出版当年[2014版] 2.901 出版当年五年平均 2.417 出版前一年[2013版] 2.685 出版后一年[2015版]

第一作者：

第一作者机构： [1]Capital Med Univ, San Bo Brain Hosp, Dept Neurosurg, Beijing, Peoples R China;

通讯作者：

通讯机构： [2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R China;

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