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Association of ideal cardiovascular health metrics and cognitive functioning: the APAC study

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收录情况： ◇ SCIE

作者：
Zhang, N.[1,2,3,4] * ; Yang, Y.[1,2,5] ; Wang, A.[2,3,4,6,7] ; Cao, Y.[8] ; Li, J.[1] ; Yang, Y.[1,2,5] ; Zhang, K.[9] ; Zhang, W.[1,2] ; Wu, S.[1,2,3,4,10] ; Wang, Z.[1] ; Zhu, M.[1] ; Zhang, Y.[1] ; Wu, S.[1,2,3,4,10] ; Wang, C.[1,2,3,4,6] ; Zhao, X.[2,3,4,6] ;
机构： [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neuropsychol & Clin Psychol, Beijing, Peoples R China; [2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [3]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [4]Beijing Inst Brain Disorders, Ctr Stroke, Beijing, Peoples R China; [5]North China Univ Sci & Technol, Grad Sch, Tangshan, Peoples R China; [6]Beijing Key Lab Translat Med Cerebrovasc Dis, Beijing, Peoples R China; [7]Capital Med Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Beijing, Peoples R China; [8]Tangshan Gongren Hosp, Dept Neurol, Tangshan, Peoples R China; [9]Tangshan Gongren Hosp, Dept Neurosurg, Tangshan, Peoples R China; [10]North China Univ Sci & Technol, Kailuan Hosp, Dept Cardiol, Tangshan, Peoples R China; [11]57 Xinhua Rd, Tangshan 063000, Peoples R China; [12]6 Tiantanxili, Beijing 100050, Peoples R China
出处：
DOI： 10.1111/ene.13056
ISSN：

关键词： cognitive functioning ideal cardiovascular health metrics Mini-Mental State Examination

摘要：
Background and purposePrevious studies have demonstrated that the components of ideal cardiovascular health (CVH) metrics are related to dementia. This study aimed to investigate the overall effects of ideal CVH metrics on cognitive functioning. MethodsInformation was collected on the seven ideal CVH metrics (smoking, body mass index, dietary intake, physical activity, blood pressure, total cholesterol and fasting blood glucose) from the Asymptomatic Polyvascular Abnormalities Community study, and cognitive functioning was assessed by the score of the Mini-Mental State Examination (MMSE). Multivariate logistic regression and linear regression models were used to assess the relationships between ideal CVH metrics and cognitive functioning. ResultsA total of 3260 (56.7% men) patients were included in this study. After adjusting for potential confounding factors, the associations between the number or score of ideal CVH metrics and cognitive impairment remained significant [odds ratio (OR) (95% confidence interval) 0.773 (0.664-0.928) and 0.904 (0.831-0.983), respectively]. In addition, there were significant linear relationships between the number or score of CVH metrics and the score of the MMSE ( = 0.211 and 0.134 respectively, P < 0.001). ConclusionsA clear inverse association was observed between the number or score of ideal CVH metrics and cognitive impairment in a Chinese population, supporting the importance of ideal CVH metrics in prevention of dementia.

语种：
外文
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PubmedID：
中科院(CAS)分区：
出版当年[2015]版：
大类 | 2 区 医学
小类 | 2 区 临床神经病学 3 区 神经科学
最新[2023]版：
大类 | 2 区 医学
小类 | 2 区 神经科学 3 区 临床神经病学
JCR分区：
出版当年[2014]版：
Q1 CLINICAL NEUROLOGY Q1 NEUROSCIENCES
最新[2023]版：
Q1 CLINICAL NEUROLOGY Q1 NEUROSCIENCES

影响因子： 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

第一作者：
第一作者机构： [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neuropsychol & Clin Psychol, Beijing, Peoples R China; [2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [3]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [4]Beijing Inst Brain Disorders, Ctr Stroke, Beijing, Peoples R China;
通讯作者：
通讯机构： [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neuropsychol & Clin Psychol, Beijing, Peoples R China; [2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [3]China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [4]Beijing Inst Brain Disorders, Ctr Stroke, Beijing, Peoples R China; [6]Beijing Key Lab Translat Med Cerebrovasc Dis, Beijing, Peoples R China; [10]North China Univ Sci & Technol, Kailuan Hosp, Dept Cardiol, Tangshan, Peoples R China; [11]57 Xinhua Rd, Tangshan 063000, Peoples R China; [12]6 Tiantanxili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Zhang N.,Yang Y.,Wang A.,et al.Association of ideal cardiovascular health metrics and cognitive functioning: the APAC study[J].EUROPEAN JOURNAL OF NEUROLOGY.2016,23(9):1447-1454.doi:10.1111/ene.13056.
APA：
Zhang, N.,Yang, Y.,Wang, A.,Cao, Y.,Li, J....&Zhao, X..(2016).Association of ideal cardiovascular health metrics and cognitive functioning: the APAC study.EUROPEAN JOURNAL OF NEUROLOGY,23,(9)
MLA：
Zhang, N.,et al."Association of ideal cardiovascular health metrics and cognitive functioning: the APAC study".EUROPEAN JOURNAL OF NEUROLOGY 23..9(2016):1447-1454

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