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Ideal Cardiovascular Health Metrics and Coronary Artery Calcification in Northern Chinese Population: A Cross-sectional Study

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收录情况: ◇ SCIE ◇ CSCD-C

机构: [1]Capital Med Univ, Beijing An Zhen Hosp, Beijing Inst Heart Lung & Blood Vasc Dis, Dept Cardiol, Beijing 100029, Peoples R China
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关键词: Ideal cardiovascular health Coronary artery calcification Atherosclerosis

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Objective Coronary artery calcification (CAC) is a well-established risk predictor of coronary heart disease events and is recognized as an indicator of subclinical atherosclerosis. Methods A cross-sectional study consisting of 2999 participants aged >= 40 years from the Jidong community of Tangshan City, an industrial and modern city of China, was conducted between 2013 and 2014 to examine the association between the ideal cardiovascular health (CVH) metrics and CAC. The ideal CVH metrics were determined based on the definition of the American Heart Association (AHA). The participants were then grouped into 4 categories according to the quartiles of their CVH metric scores as follows: first quartile (0-2), second quartile (3), third quartile (4), and fourth quartile (5-7). CAC was assessed by using high-pitch dual-source CT, and patients were identified based on thresholds of 0, 10, 100, or 400 Agatston units, as per common practice. Results The prevalence of subclinical atherosclerosis was 15.92%, 13.85%, 6.76%, and 1.93%, determined by using the CAC scores at thresholds of 0, 10, 100, and 400 Agatston units, respectively. Compared with the group in the first quartile, the other three CVH groups had a lower odds ratio of CAC >0 after adjusting for age, sex, income level, education level, and alcohol use in the logistic regression analysis. The odds ratios in these groups were 0.86 [95% confidence interval (CI), 0.63-1.17; P<0.05], 0.75 (95% CI, 0.55-1.02; P<0.05), and 0.49 (95% CI, 0.35-0.69; P<0.05), respectively. These associations of CAC with the CVH metrics were consistent when different CAC cutoff scores were used (0, 10, 100, or 400). Conclusion The participants with more-ideal cardiovascular metrics had a lower prevalence of subclinical atherosclerosis determined according to CAC score. Maintaining an ideal cardiovascular health may be valuable in the prevention of atherosclerosis in the general population.

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出版当年[2015]版:
大类 | 4 区 环境科学与生态学
小类 | 4 区 环境科学 4 区 公共卫生、环境卫生与职业卫生
最新[2023]版:
大类 | 3 区 医学
小类 | 4 区 环境科学 4 区 公共卫生、环境卫生与职业卫生
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出版当年[2014]版:
Q2 ENVIRONMENTAL SCIENCES Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版:
Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Q2 ENVIRONMENTAL SCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [1]Capital Med Univ, Beijing An Zhen Hosp, Beijing Inst Heart Lung & Blood Vasc Dis, Dept Cardiol, Beijing 100029, Peoples R China
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通讯机构: [1]Capital Med Univ, Beijing An Zhen Hosp, Beijing Inst Heart Lung & Blood Vasc Dis, Dept Cardiol, Beijing 100029, Peoples R China
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