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Ideal cardiovascular health and incident hypertension The longitudinal community-based Kailuan study

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机构: [1]Tianjin Med Univ, Dept Cardiol, Tianjin Ctr Hosp 1, Clin Med Coll, Tianjin, Peoples R China; [2]North China Univ Sci & Technol, Kailuan Hosp, Dept Cardiol, Tangshan 063000, Peoples R China; [3]North China Univ Sci & Technol, Tangshan Peoples Hosp, Dept Cardiol, Tangshan, Peoples R China; [4]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [5]Capital Med Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Beijing, Peoples R China; [6]Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Heidelberg, Germany
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关键词: arterial hypertension hypertension ideal cardiovascular health Kailuan study

摘要:
Ideal cardiovascular health (CVH) has been defined by the American Heart Association as the absence of disease and presence of 7 key health factors. Since it is unknown whether cumulative exposure to CVH reduces the risk of developing arterial hypertension, we prospectively examined the potential association between cumulative CVH (cumCVH) score (except for blood pressure metrics) and incident hypertension. Of the 101,510 participants with an age range of 18 to 98 years in this longitudinal community-based Kailuan study, our cohort included those 15,014 participants without hypertension at baseline and who had follow-up examinations 2, 4, and 6 years later. CumCVH was calculated as the summed CVH score for each examination multiplied by the time between the 2 examinations (points x year). Based on the cumCVH score, the study population was stratified into groups of <44 points, 44 to 48 points, 49 to 54 points, 55 to 59 points, and >= 60 points. Incidence of hypertension ranged from 16.76% in the lowest cumCVH category to 11.52% in the highest cumCVH category. After adjusting for age, sex, education level, income level, high-sensitivity C-reactive protein concentration, uric acid concentration, resting heart rate, parental history of hypertension at baseline, and medication usage before the third follow-up examination, participants in the highest cumCVH category had a significantly reduced risk of incident hypertension compared with those in the lowest cumCVH category (adjusted odds ratio 0.60, 95% confidence interval 0.50-0.71). For every increase in category based on the cumCVH score, the risk of hypertension decreased by approximately 2% (odds ratio 0.98, 95% confidence interval 0.97-0.98). The effect was consistent across sex and age groups. A higher cumCVH score is associated with a lower risk of incident

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出版当年[2015]版:
大类 | 2 区 医学
小类 | 2 区 医学:内科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
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出版当年[2014]版:
Q1 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q2 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [1]Tianjin Med Univ, Dept Cardiol, Tianjin Ctr Hosp 1, Clin Med Coll, Tianjin, Peoples R China; [2]North China Univ Sci & Technol, Kailuan Hosp, Dept Cardiol, Tangshan 063000, Peoples R China;
通讯作者:
通讯机构: [1]Tianjin Med Univ, Dept Cardiol, Tianjin Ctr Hosp 1, Clin Med Coll, Tianjin, Peoples R China; [2]North China Univ Sci & Technol, Kailuan Hosp, Dept Cardiol, Tangshan 063000, Peoples R China;
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