Impaired Glucose Regulation Predicted 1-Year Mortality of Chinese Patients With Ischemic Stroke Data From Abnormal Glucose Regulation in Patients With Acute Stroke Across China
Background and Purpose It remains uncertain if impaired glucose regulation (IGR) as a predictor for stroke outcomes. This study aimed at observing the effect of IGR on the 1-year outcomes in Chinese patients with ischemic stroke. Methods Patients with acute ischemic stroke were recruited consecutively in multihospitals across China. Oral glucose tolerance test was performed to identify IGR. Cox proportion hazard model was performed to investigate the effect of IGR on 1-year mortality or stroke recurrence in patients with ischemic stroke. Results The study recruited 2639 patients with ischemic stroke. IGR was shown as an independent risk factor for the mortality of patients with ischemic stroke (hazard ratio [95% confidence interval], 3.088 [1.386-6.884]; P=0.006). However, IGR showed no significant effects on the dependency or stroke recurrence of patients (P=0.540 and 0.618, respectively). Conclusions IGR was an independent predictor for the mortality of patients with ischemic stroke. IGR should be highlighted and intervened actively in the patients with ischemic stroke.
基金:
Ministry of Science and TechnologyMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT); Ministry of Health of the People's Republic of China; National S&T Major Project of China [2011BAI08B02]
第一作者机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing 100050, Peoples R China;
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing 100050, Peoples R China;[2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, 6 Tiantanxili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Jia Qian,Liu Gaifen,Zheng Huaguang,et al.Impaired Glucose Regulation Predicted 1-Year Mortality of Chinese Patients With Ischemic Stroke Data From Abnormal Glucose Regulation in Patients With Acute Stroke Across China[J].STROKE.2014,45(5):1498-1500.doi:10.1161/STROKEAHA.113.002977.
APA:
Jia, Qian,Liu, Gaifen,Zheng, Huaguang,Zhao, Xingquan,Wang, Chunxue...&Wang, Yongjun.(2014).Impaired Glucose Regulation Predicted 1-Year Mortality of Chinese Patients With Ischemic Stroke Data From Abnormal Glucose Regulation in Patients With Acute Stroke Across China.STROKE,45,(5)
MLA:
Jia, Qian,et al."Impaired Glucose Regulation Predicted 1-Year Mortality of Chinese Patients With Ischemic Stroke Data From Abnormal Glucose Regulation in Patients With Acute Stroke Across China".STROKE 45..5(2014):1498-1500