The effectiveness of antibiotic prophylaxis (AP) in craniotomies has been clarified through the accumulation of evidence and increased antibiotic knowledge. This paper focuses on the use of AP in craniotomies during different historical periods and collects highly relevant evidence on this issue. This review surveys different AP guidelines and explains why cefazolin was selected by most guidelines. Recent prominent topics, including strategies to update and implement guidelines and antibiotic efficacy in postoperative meningitis and surveillance and decolonization therapies for methicillin-resistant Staphylococcus aureus, are discussed.
第一作者机构：[1]Capital Med Univ, Dept Neurosurg, Beijing Tiantan Hosp, Beijing 100050, Peoples R China;[2]Univ Groningen, Univ Med Ctr Groningen, Dept Neurosurg, NL-9713 GZ Groningen, Netherlands;
通讯作者：
通讯机构：[1]Capital Med Univ, Dept Neurosurg, Beijing Tiantan Hosp, Beijing 100050, Peoples R China;[2]Univ Groningen, Univ Med Ctr Groningen, Dept Neurosurg, NL-9713 GZ Groningen, Netherlands;[4]Capital Med Univ, Dept Neurosurg, Beijing Tiantan Hosp, Tiantan Xili 6, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Liu Weiming,Ni Ming,Zhang Yuewei,et al.Antibiotic prophylaxis in craniotomy: a review[J].NEUROSURGICAL REVIEW.2014,37(3):407-414.doi:10.1007/s10143-014-0524-z.
APA：
Liu, Weiming,Ni, Ming,Zhang, Yuewei&Groen, Rob J. M..(2014).Antibiotic prophylaxis in craniotomy: a review.NEUROSURGICAL REVIEW,37,(3)
MLA：
Liu, Weiming,et al."Antibiotic prophylaxis in craniotomy: a review".NEUROSURGICAL REVIEW 37..3(2014):407-414
