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Childhood absence epilepsy: Elctroclinical features and diagnostic criteria

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机构： [a]Department of Pediatrics, Peking University First Hospital, No. 1, of Xian Men Street, Xicheng District, Beijing, PR, 100034, China [b]Bayi Children's Hospital Affiliated to General Hospital of Beijing District, PLA, PR, 100710, China [c]Department of Pediatrics, First Hospital of Jilin University, Changchun, PR, 130021, China

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关键词： Childhood absence epilepsy Diagnosis Electroencephalogram

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Objective: To analyze the electroclinical features of children with childhood absence epilepsy (CAE) and discuss the diagnostic criteria for CAE. Methods: The video-electroencephalogram (VEEG) database in our hospital was searched using "absence seizures" and "3-Hz generalized spike and waves (GSW)" as key-words. Other epileptic syndromes with typical absence seizures were carefully excluded. Children meeting the CAE diagnostic criteria of the International League Against Epilepsy (ILAE) in 1989 were further evaluated with the diagnostic criteria proposed by Panayiotopoulos in 2005. Results: Totally 37 children met the 1989 ILAE criteria of CAE. The onset age of absence seizures ranged from 3 to 11 years. All patients had frequent absence seizures (5-60 times per day). Two patients (5.4%) had generalized tonic-clonic seizures. Hyperventilation induced absences in all patients. VEEG confirmed that 7 patients (18.9%) had only simple absences, 25 patients (67.6%) had only complex absences, and 5 patients (13.5%) had both simple and complex absences. Ictal EEG showed 3. Hz GSW discharges in all patients. The seizure duration ranged from 3 to 40 s. Four patients (10.8%) had two spikes per wave in ictal EEG. GSW fragments were found in 29 patients (78.4%) during sleep. Interictal polyspikes and waves were present in 17 patients (45.9%). Focal discharges predominantly in the anterior regions, were found in 22 patients (56.8%). Only 7 patients (18.9%) met the diagnostic criteria proposed by Panayiotopoulos in 2005. Conclusions: Few patients meeting the 1989 ILAE diagnostic criteria for CAE meet the new diagnostic criteria proposed by Panayiotopoulos in 2005. The new criteria for CAE are too strict to appropriately classify some patients. © 2010 The Japanese Society of Child Neurology.

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出版当年[2010]版：

大类 | 4 区医学

小类 | 4 区临床神经病学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区儿科

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出版当年[2009]版：

Q3 CLINICAL NEUROLOGY

最新[2023]版：

Q2 PEDIATRICS Q3 PEDIATRICS Q3 CLINICAL NEUROLOGY Q4 CLINICAL NEUROLOGY

影响因子： 1.5 最新[2023版] 1.5 最新五年平均 1.743 出版当年[2009版] 1.657 出版当年五年平均 1.401 出版前一年[2008版] 1.979 出版后一年[2010版]

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