Objective To explore the risk factors for Guillain-barre syndrome. Methods Case-control study design was used in 51 cases of Guillain-barre syndrome, and 51 matched controls. All of the 51 cases in this study had been examined by electrophysiology. Serum IgG antibodies specific for C. jejuni were determined in all the subjects by ELISA. Each case and control were interviewed using an ad hoc questionnaire, including his/her demographic information, onset of the illness, their personal hygiene and so on. Results The study showed that Guillain-barre syndrome was associated with a few factors, such as polio vaccine immunization before onset of illness (OR=7.27), no hand washing after defecation and before meals (OR=6.15). Infection of C jejuni was strongly associated with the illness (OR=9.5, P<0.001). Conclusion It is suggested that occurrence of Guillain-barre syndrome may correlate to infection of C. jejuni and poor personal hygiene in children.
语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[2002]版：
无
最新[2023]版：
大类|3 区医学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
JCR分区：
出版当年[2001]版：
Q4ENVIRONMENTAL SCIENCESQ4PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[1]Chinese Acad Med Sci, Peking Union Med Coll, Sch Basic Med, Dept Epidemiol, Beijing 100005, Peoples R China;[2]Beijing Childrens Hosp, Dept Neurol, Beijing 100045, Peoples R China;[3]Norman Bethune Univ Med Sci, Dept Epidemiol, Changchun 130021, Peoples R China;[4]Norman Bethune Univ Med Sci, Hosp 1st, Dept Pediat, Changchun 130021, Peoples R China;[5]Mongolia Med Coll, Hosp 1st, Dept Pediat, Huhehot 010050, Peoples R China
通讯作者：
通讯机构：[1]Chinese Acad Med Sci, Peking Union Med Coll, Sch Basic Med, Dept Epidemiol, Beijing 100005, Peoples R China;[2]Beijing Childrens Hosp, Dept Neurol, Beijing 100045, Peoples R China;[3]Norman Bethune Univ Med Sci, Dept Epidemiol, Changchun 130021, Peoples R China;[4]Norman Bethune Univ Med Sci, Hosp 1st, Dept Pediat, Changchun 130021, Peoples R China;[5]Mongolia Med Coll, Hosp 1st, Dept Pediat, Huhehot 010050, Peoples R China
推荐引用方式(GB/T 7714)：
Liu GF,Wu ZL,Wu HS,et al.A case-control study on children with Guillain-Barre syndrome in North China[J].BIOMEDICAL AND ENVIRONMENTAL SCIENCES.2003,16(2):105-111.
APA：
Liu, GF,Wu, ZL,Wu, HS,Wang, QY,Zhao-Ri, GT...&Zheng, JD.(2003).A case-control study on children with Guillain-Barre syndrome in North China.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,16,(2)
MLA：
Liu, GF,et al."A case-control study on children with Guillain-Barre syndrome in North China".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 16..2(2003):105-111
