BACKGROUND Cellulose acetate polymer (CAP) is a new liquid embolic material that has been used experimentally in intravascular treatment of intracranial aneurysms. But this compound is still controversial in some aspects such as safety, efficiency, and histological changes. In this study, we reevaluated the material with regard to intravascular treatment of aneurysms. METHODS The carotid arteries of rats and experimental aneurysms in canines were embolized with CAP. The effects of CAP were evaluated according to angiographic and histological results. RESULTS A strong chemo-corrosive effect was observed. This led to severe damage to vessels and rupture of two thrombosed canine aneurysm models. There were significant technical difficulties including out-flow of CAP and a high rate of occlusion of the parent arteries. CONCLUSIONS We conclude that currently CAP is not an ideal embolic material for intracranial aneurysms. Further tests and improvements are needed before it can be widely used clinically (C) 2001 by Elsevier Science Inc.
第一作者机构：[1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China;[2]Shandong Med Imag Inst, Beijing, Peoples R China;[3]Beijing Neurosurg Inst, 6 Tiantan Xili, Beijing 100050, Peoples R China
通讯作者：
通讯机构：[1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China;[2]Shandong Med Imag Inst, Beijing, Peoples R China;[3]Beijing Neurosurg Inst, 6 Tiantan Xili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Yang XJ,Wu ZX,Li YX,et al.Re-evaluation of cellulose acetate polymer: Angiographic findings and histological studies[J].SURGICAL NEUROLOGY.2001,55(2):116-122.doi:10.1016/S0090-3019(00)00331-1.
APA：
Yang, XJ,Wu, ZX,Li, YX,Tang, J,Sun, YL...&Yin, K.(2001).Re-evaluation of cellulose acetate polymer: Angiographic findings and histological studies.SURGICAL NEUROLOGY,55,(2)
MLA：
Yang, XJ,et al."Re-evaluation of cellulose acetate polymer: Angiographic findings and histological studies".SURGICAL NEUROLOGY 55..2(2001):116-122
