机构:[1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China;研究所北京市神经外科研究所首都医科大学附属天坛医院[2]Shandong Med Image Inst, Shandong 320057, Peoples R China;[3]6 Tiantan Xili, Beijing 100050, Peoples R China
Objective To develop a Chinese-made electrolytic detachable coil (CEDC) that would allow patients to enjoy the benefit of electrolytic detachable coil without having to rely on the expensive Guglielmi detachable coil (GDC), and to test the safety and efficiency of CEDC. Methods Radiopacity of the marker of the CEDC was tested. The anti-strain force of coils and connection points were measured. In vitro and in vivo electrolyses were conducted. We produced 21 aneurysm models including lateral, bifurcation, and terminal aneurysm models, and embolized 18 models with CEDC. Results Radiopacity of the marker was satisfactory. Anti-strain of the coil and the connection point have shown the safety and efficiency of CEDC. Electrolysis in vitro and vivo, was similar to that of GDC. 83% of the aneurysm models were completely occluded. Coils were found to induce thrombosis in the aneurysm cavity, and could lead to a new endothelium over the entrance of the aneurysm, with organized tissue replacing thrombosis in 2 months. Conclusions CEDC is as efficient and safe as GDC. The marker, the ability to induce thrombosis inside the sac and the growth of new endothelium over the orifice are very satisfactory.
第一作者机构:[1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China;[2]Shandong Med Image Inst, Shandong 320057, Peoples R China;[3]6 Tiantan Xili, Beijing 100050, Peoples R China
通讯作者:
通讯机构:[1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China;[2]Shandong Med Image Inst, Shandong 320057, Peoples R China;[3]6 Tiantan Xili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Yang XJ,Wu ZX,Wang CC,et al.Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model[J].CHINESE MEDICAL JOURNAL.2000,113(10):921-926.
APA:
Yang, XJ,Wu, ZX,Wang, CC,Li, YX,Liu, ZQ...&Yin, K.(2000).Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model.CHINESE MEDICAL JOURNAL,113,(10)
MLA:
Yang, XJ,et al."Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model".CHINESE MEDICAL JOURNAL 113..10(2000):921-926