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Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model

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收录情况: ◇ SCIE ◇ 中华系列

机构: [1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China; [2]Shandong Med Image Inst, Shandong 320057, Peoples R China; [3]6 Tiantan Xili, Beijing 100050, Peoples R China
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关键词: aneurysms electrolytic detachable coils

摘要:
Objective To develop a Chinese-made electrolytic detachable coil (CEDC) that would allow patients to enjoy the benefit of electrolytic detachable coil without having to rely on the expensive Guglielmi detachable coil (GDC), and to test the safety and efficiency of CEDC. Methods Radiopacity of the marker of the CEDC was tested. The anti-strain force of coils and connection points were measured. In vitro and in vivo electrolyses were conducted. We produced 21 aneurysm models including lateral, bifurcation, and terminal aneurysm models, and embolized 18 models with CEDC. Results Radiopacity of the marker was satisfactory. Anti-strain of the coil and the connection point have shown the safety and efficiency of CEDC. Electrolysis in vitro and vivo, was similar to that of GDC. 83% of the aneurysm models were completely occluded. Coils were found to induce thrombosis in the aneurysm cavity, and could lead to a new endothelium over the entrance of the aneurysm, with organized tissue replacing thrombosis in 2 months. Conclusions CEDC is as efficient and safe as GDC. The marker, the ability to induce thrombosis inside the sac and the growth of new endothelium over the orifice are very satisfactory.

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出版当年[1999]版:
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
JCR分区:
出版当年[1998]版:
Q4 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q1 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[1998版] 出版当年五年平均 出版前一年[1997版] 出版后一年[1999版]

第一作者:
第一作者机构: [1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China; [2]Shandong Med Image Inst, Shandong 320057, Peoples R China; [3]6 Tiantan Xili, Beijing 100050, Peoples R China
通讯作者:
通讯机构: [1]Beijing Neurosurg Inst, Beijing 100050, Peoples R China; [2]Shandong Med Image Inst, Shandong 320057, Peoples R China; [3]6 Tiantan Xili, Beijing 100050, Peoples R China
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