机构:[1]Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Department of Cardiology, 12th ward, Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, China.临床科室心脏内科中心首都医科大学附属安贞医院[2]Department of Geriatric Medicine and Gerontology, Hainan General Hospital, Hainan, China.[3]Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.临床科室急诊危重症中心首都医科大学附属安贞医院
Adipose tissue stores energy and is the largest endocrine organ in the body, producing several adipokines. However, among these adipokines, few play a role in the positive metabolism that promotes good health. Secreted frizzled-related protein (Sfrp)-5, an antagonist that directly binds to Wnt, has attracted interest due to its favorable effects on atherosclerotic cardiovascular disease (ASCVD). This review focuses on Sfrp5 biology and the roles of the Sfrp5/Wnt system in ASCVD.
基金:
Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [ZYLX201303, XMLX201601]; National Key Research and Development Program of China [2017YFC0908800]; Beijing Municipal Administration of Hospitals' Ascent Plan [DFL20150601]; [SML20180601]
第一作者机构:[1]Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Department of Cardiology, 12th ward, Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, China.[2]Department of Geriatric Medicine and Gerontology, Hainan General Hospital, Hainan, China.
共同第一作者:
通讯作者:
通讯机构:[1]Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Department of Cardiology, 12th ward, Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, China.[*1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
推荐引用方式(GB/T 7714):
Tong Shan,Ji Qingwei,Du Yu,et al.Sfrp5/Wnt Pathway: A Protective Regulatory System in Atherosclerotic Cardiovascular Disease[J].JOURNAL OF INTERFERON AND CYTOKINE RESEARCH.2019,39(8):472-482.doi:10.1089/jir.2018.0154.
APA:
Tong, Shan,Ji, Qingwei,Du, Yu,Zhu, Xiaogang,Zhu, Caizhong&Zhou, Yujie.(2019).Sfrp5/Wnt Pathway: A Protective Regulatory System in Atherosclerotic Cardiovascular Disease.JOURNAL OF INTERFERON AND CYTOKINE RESEARCH,39,(8)
MLA:
Tong, Shan,et al."Sfrp5/Wnt Pathway: A Protective Regulatory System in Atherosclerotic Cardiovascular Disease".JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 39..8(2019):472-482