Association of peak atrial longitudinal strain with atrial fibrillation recurrence in patients with chronic lung diseases following radiofrequency ablation
机构:[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University,Beijing, China首都医科大学附属同仁医院[2]Ultrasound Department, Beijing Anzhen Hospital, Capital Medical University,Beijing, China医技科室综合超声科首都医科大学附属安贞医院[3]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing, China临床科室心脏内科中心首都医科大学附属安贞医院
Background: Strain was shown associated with atrial fibrillation (AF) recurrence after radiofrequency ablation (RFA), but data on AF patients complicated with chronic lung diseases (CLD) were rare. Aim: This study was designed to evaluate the relationship of baseline atrial function with AF recurrence in these patients using speckle-tracking echocardiography. Methods: Average strain values (median: 2 days before RFA) were calculated for 87 AF patients (Mean age: 61.91 years, male: 71.26%) with CLD undergoing RFA from 2013 to 2014. Of these patients, 25 (28.74%) experienced AF recurrence during a mean follow up of 10.3 months. Results: Peak right atrial longitudinal strain (R-PALS) was associated with peak left atrial longitudinal strain (L-PALS, Standardised beta = 0.45, P < 0.001) in multivariate linear regression. Multivariate Cox regression analysis showed R-PALS was associated with AF recurrence (hazard ratio, 0.86; 95% confidence interval (CI), 0.78-0.96, P = 0.005) in CLD. Patients with R-PALS >= 14.69% had higher AF free rate compared with R-PALS<14.69% using Kaplan-Meier analysis (log-rank, P < 0.001). R-PALS had similar C-index compared to L-PALS (difference: 0.03, 95% CI: -0.06-0.12, P = 0.53) and combined R-PALS and L-PALS (difference: 0.005, 95% CI: -0.04-0.05, P = 0.84) associated with AF recurrence in CLD. Conclusion: R-PALS, L-PALS and combined R-PALS and L-PALS are important factors associated with AF recurrence following RFA in patients with CLD.
基金:
This study was supported by grants from Beijing
Tongren Hospital, Capital Medical University (No. 2016-YJJBJRC-
010), Beijing Municipal Administration of Hospitals
Clinical medicine Development of special funding support
(No. XMLX201604), the National Key Research and
Development Program of China (2016YFC0900901), the
National Science Foundation of China (81530016), Beijing
Municipal Commission of Science and Technology (D151100
002215003, D151100002215004). The construction of the
China-AF was also supported by grants from BMS, Pfizer,
Johnson & Johnson, BI, and Bayer.
第一作者机构:[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University,Beijing, China
通讯作者:
通讯机构:[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University,Beijing, China[3]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing, China[*1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, No.1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing 100730, China.
推荐引用方式(GB/T 7714):
Ying Bai,Ying Zhao,Jie Li,et al.Association of peak atrial longitudinal strain with atrial fibrillation recurrence in patients with chronic lung diseases following radiofrequency ablation[J].INTERNAL MEDICINE JOURNAL.2018,48(7):851-859.doi:10.1111/imj.13768.
APA:
Ying Bai,Ying Zhao,Jie Li,Ying Zhang,Rong Bai...&Chang Sheng Ma.(2018).Association of peak atrial longitudinal strain with atrial fibrillation recurrence in patients with chronic lung diseases following radiofrequency ablation.INTERNAL MEDICINE JOURNAL,48,(7)
MLA:
Ying Bai,et al."Association of peak atrial longitudinal strain with atrial fibrillation recurrence in patients with chronic lung diseases following radiofrequency ablation".INTERNAL MEDICINE JOURNAL 48..7(2018):851-859