机构：[a]Evidence-Based Medical Center,Xuanwu Hospital, Capital Medical University首都医科大学宣武医院[b]Central Laboratory,Xuanwu Hospital, Capital Medical University首都医科大学宣武医院[c]Departments of Neurology,Xuanwu Hospital, Capital Medical University神经科系统神经内科首都医科大学宣武医院[d]Departments of Vascular Ultrasound,Xuanwu Hospital, Capital Medical University首都医科大学宣武医院[e]Departments of Neurobiology,Xuanwu Hospital, Capital Medical University首都医科大学宣武医院[f]Departments of Ophthalmology, Xuanwu Hospital, Capital Medical University,外科系统眼科首都医科大学宣武医院[g]Department of Echocardiography, Beijing Anzhen Hospital,医技科室超声心动科首都医科大学附属安贞医院[h]Department of Gerontology, Fuxing Hospital, Capital Medical University,[i]Beijing Geriatric Medical Research Center,[j]Key Laboratory of Neurodegenerative Diseases,Ministry of Education,[k]Beijing Municipal Key Laboratory of Clinical Epidemiology,[l]State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science, and Peking Union Medical College,[m]Department of Neurology, Beijing Tsinghua Changgung Hospital Medical Center, Tsinghua University, Beijing , China
The Cardiovascular and Cognitive Health Study (CCHS-Beijing) is a population-based study of cardiovascular disease (CVD) and cognitive impairment in adults aged 55 and older in Beijing. The main aims of the study are to investigate the prevalence rates of CVD, asymptomatic atherosclerosis, and cognitive impairment, as well as validate the risk factors related to the onset and development of CVD, Alzheimer's disease (AD) and mild cognitive impairment (MCI). The study was designed to detect the traditional and new risk factors in this age group. Participants were recruited randomly from residential regions in the greater Beijing municipality area based on the average levels of development in Beijing, China in 2012 (based on socioeconomic, demographic, and geographical characteristics). Thorough physical and laboratory examination were performed at baseline (also the cross-sectional survey) to identify the risk factors such as hypertension, dyslipidemia, diabetes, as well as newly defined risk-factors like elevated homocysteine, high sensitivity C-reactive protein, and urine micro-albumin. Subclinical disease of the cerebral vasculature included atherosclerosis of carotid arteries, intracranial arteries, and retinal vessels. Subclinical cardiac diseases included left ventricular enlargement, arrhythmias, chamber hypertrophy and myocardial ischemia. Blood pressure was documented using the ankle-arm method. In addition, neuropsychological assessments were performed for all subjects aged 65 and above. Baseline evaluation began during the period August 2013 to December 2014. Follow-up examination will occur in 5 years. The initial and recurrent CVD, AD and MCI events will be verified and validated during the follow-up period. (C) 2016 S. Karger AG, Basel
基金：
the Commission of Science and Technology of Beijing (Grant No. D121100004912002),
National Science and Technology Support Program (Grant No. 2011BAI11B01)
the Capital Health Research and Development of Special (Grant No. 2014-1-1031).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2015]版：
大类|3 区医学
小类|3 区临床神经病学3 区公共卫生、环境卫生与职业卫生
最新[2023]版：
大类|3 区医学
小类|3 区公共卫生、环境卫生与职业卫生4 区临床神经病学
JCR分区：
出版当年[2014]版：
Q2CLINICAL NEUROLOGYQ2PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版：
Q2CLINICAL NEUROLOGYQ2PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[a]Evidence-Based Medical Center,Xuanwu Hospital, Capital Medical University[i]Beijing Geriatric Medical Research Center,[j]Key Laboratory of Neurodegenerative Diseases,Ministry of Education,[k]Beijing Municipal Key Laboratory of Clinical Epidemiology,[*1]Evidence-based Medical Center, Xuanwu Hospital, Capital Medical University, #45 Changchun Street, Beijing 100053 (China)
通讯作者：
通讯机构：[a]Evidence-Based Medical Center,Xuanwu Hospital, Capital Medical University[i]Beijing Geriatric Medical Research Center,[j]Key Laboratory of Neurodegenerative Diseases,Ministry of Education,[k]Beijing Municipal Key Laboratory of Clinical Epidemiology,[*1]Evidence-based Medical Center, Xuanwu Hospital, Capital Medical University, #45 Changchun Street, Beijing 100053 (China)
推荐引用方式(GB/T 7714)：
Xianghua Fang,Zhengwu Wang,Chunxiu Wang,et al.Cardiovascular and Cognitive Health Study in Middle-Aged and Elderly Residents of Beijing (CCHS-Beijing): Design and Rationale[J].NEUROEPIDEMIOLOGY.2016,46(3):182-190.doi:10.1159/000443707.
APA：
Xianghua Fang,Zhengwu Wang,Chunxiu Wang,Jian Wu,Ya Yang...&Shaochen Guan.(2016).Cardiovascular and Cognitive Health Study in Middle-Aged and Elderly Residents of Beijing (CCHS-Beijing): Design and Rationale.NEUROEPIDEMIOLOGY,46,(3)
MLA：
Xianghua Fang,et al."Cardiovascular and Cognitive Health Study in Middle-Aged and Elderly Residents of Beijing (CCHS-Beijing): Design and Rationale".NEUROEPIDEMIOLOGY 46..3(2016):182-190
