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Superparamagnetic Iron Oxide Nanoparticles as Magnetic Resonance Imaging Contrast Agent for Myocardial Infarction

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机构: [1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Beijing An Zhen Hosp, Dept Radiol, Beijing 100029, Peoples R China; [2]Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China; [3]Ocean Univ China, Inst Mat Sci & Engn, Qingdao 266100, Shandong, Peoples R China; [4]Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Henan, Peoples R China
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关键词: Myocardial Infarction Superparamagnetic Iron Oxide Nanoparticles Macrophages Infarcted Tissue Magnetic Resonance Imaging

摘要:
Citric acid coated superparamagnetic iron oxide nanoparticles (CA-SPIONs) are synthesized by co-precipitation method and citric acid is used to stabilize nanoparticles and provide significantly small nanoparticles. CA-SPIONs have small size, favorable colloidal stability and excellent magnetic properties. As contrast agent, on the one hand CA-SPIONs have biocompatibility and can be endocytosed by macrophages, on the other hand CA-SPIONs have the ability of MRI in the infarcted tissue of myocardial infarction.

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出版当年[2015]版:
大类 | 4 区 生物
小类 | 4 区 细胞与组织工程
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 细胞与组织工程
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出版当年[2014]版:
Q4 CELL & TISSUE ENGINEERING
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第一作者机构: [1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Beijing An Zhen Hosp, Dept Radiol, Beijing 100029, Peoples R China;
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通讯机构: [1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Beijing An Zhen Hosp, Dept Radiol, Beijing 100029, Peoples R China; [2]Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China;
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