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Four-year imaging follow-up of a homozygous familial hypercholesterolaemia patient: atherosclerosis ingravescence and coronary flow velocity reserve reduced gradually. Case report

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收录情况： ◇ SCIE

作者：

机构： [1]Capital Med Univ, Dept Echocardiog, Beijing Anzhen Hosp, Beijing 100029, Peoples R China; [2]Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [3]Capital Med Univ, Beijing AnZhen Hosp, Beijing Inst Heart Lung & Blood Vessel Dis,Dept A, Key Lab Remodeling Related Cardiovasc Dis,Minist, Beijing 100029, Peoples R China; [4]Capital Med Univ, Beijing An Zhen Hosp, Dept Nucl Med, Beijing 100029, Peoples R China; [5]Capital Med Univ, Dept Echocardiog, Beijing Anzhen Hosp, 2 Anzhen Rd, Beijing 100029, Peoples R China

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关键词： familial hypercholesterolemia atherosclerosis echocardiography coronary flow velocity reserve

摘要：

Homozygous familial hypercholesterolemia (HoFH) is a rare heredity disease in which severe cardiovascular atherosclerosis develops from birth due to severe low density lipoprotein-receptor (LDL-R) defects inherited from both heterozygous-carriers of FH (HeFH) parents. This case describes a HoFH patient who underwent medical imaging examination for 4 years over a course of treatment. In addition to the imaging techniques which demonstrated the development of cardiovascular atherosclerosis ingravescent, transthoracic Doppler echocardiography noninvasively and accurately detected the position of atherosclerotic calcifications and evaluated the hemodynamicsof the coronary flow. Analysis showed the patient had a significantly lower coronary flow velocity reserve due to plaques compromising coronary artery ostia.

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出版当年[2014]版：

无

最新[2023]版：

大类 | 4 区医学

小类 | 4 区声学 4 区核医学

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出版当年[2013]版：

无

最新[2023]版：

Q2 ACOUSTICS Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子： 1.8 最新[2023版] 1.7 最新五年平均 0 出版当年[2013版] 0 出版当年五年平均 0 出版前一年[2012版] 1.108 出版后一年[2014版]

第一作者：

第一作者机构： [1]Capital Med Univ, Dept Echocardiog, Beijing Anzhen Hosp, Beijing 100029, Peoples R China;

通讯作者：

通讯机构： [1]Capital Med Univ, Dept Echocardiog, Beijing Anzhen Hosp, Beijing 100029, Peoples R China; [2]Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [5]Capital Med Univ, Dept Echocardiog, Beijing Anzhen Hosp, 2 Anzhen Rd, Beijing 100029, Peoples R China

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