Purpose This study aimed to determine blood pressure characteristics and long-term progress in patients with white coat hypertension (WCH) and obstructive sleep apnea (OSA). Methods Systolic blood pressure (SBP) and diastolic blood pressure (DBP) and sleep test results over a period of 26 months were analyzed from WCH patients with OSA (n = 28), WCH patients (n = 23), and healthy control subjects (n = 27). Results At the end of observation, WCH patients with OSA presented significantly increased daytime and nighttime BP and lower diurnal difference of SBP (all Ps < 0.05) and the increased rate of "non-dipper" status (SBP 28.6 %, DBP 32.1 %) was significantly higher when compared with WCH and control groups (all Ps < 0.01). Sustained hypertension was observed in 42.8 % of the WCH patients with OSA, which was significantly higher than that in the WCH and control groups (Ps < 0.01) and was predicted by non-dipper status via 24-h ambulatory SBP/DBP monitoring (Ps < 0.05). Conclusion WCH may represent a prehypertension status, which could develop into sustained hypertension with OSA.
第一作者机构：[1]Capital Univ Med Sci, Beijing Tong Ren Hosp, Ctr Cardiovasc, Beijing 100730, Peoples R China;
通讯作者：
通讯机构：[1]Capital Univ Med Sci, Beijing Tong Ren Hosp, Ctr Cardiovasc, Beijing 100730, Peoples R China;
推荐引用方式(GB/T 7714)：
Li Li,Guo Li-zhu,Li Jie,et al.White coat hypertension and obstructive sleep apnea[J].SLEEP AND BREATHING.2015,19(4):1199-1203.doi:10.1007/s11325-015-1137-7.
APA：
Li, Li,Guo, Li-zhu,Li, Jie,Wang, Ying,Liu, Xin...&Ma, Chang-sheng.(2015).White coat hypertension and obstructive sleep apnea.SLEEP AND BREATHING,19,(4)
MLA：
Li, Li,et al."White coat hypertension and obstructive sleep apnea".SLEEP AND BREATHING 19..4(2015):1199-1203
