Objective: The current study aims to evaluate the diagnostic accuracy of two-dimensional echocardiography combined with enhanced flow (e-flow) imaging for fetal heart malformation. Materials and Methods: A total of 1,639 pregnant women were enrolled. They were examined using fetal echocardiography combined e-flow. The obtained results were compared with those by postnatal examination or post-induction autopsy. Results: Complete data were obtained from 1,286 out of the 1,639 fetuses (78.46%). Two-dimensional echocardiography combined with e-flow imaging had sensitivity, specificity, a misdiagnosis rate, and a missed diagnosis rate of 98.0%, 99.3%, 2.0%, and 0.7%, respectively. It has a consistency evaluation Kappa value of 0.970 (p = 0.000). Conclusion: Two-dimensional echocardiography combined with e-flow is an accurate and reliable diagnostic method for fetal heart malformation. It has high sensitivity and specificity.
基金：
National Natural Science FundNational Natural Science Foundation of China [81171350]
第一作者机构：[1]Capital Med Univ, Beijing Anzhen Hosp, Dept Ultrasound Med, Beijing 100029, Peoples R China;
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Anzhen Hosp, Dept Ultrasound Med, Beijing 100029, Peoples R China;[2]Henan Prov Hosp, Dept Ultrasound Med, Zhengzhou, Peoples R China
推荐引用方式(GB/T 7714)：
Liu L.,He Y.,Li Z.,et al.Application of two-dimensional echocardiography combined with enhanced flow in diagnosing fetal heart malformation[J].CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY.2014,41(2):195-201.doi:10.12891/ceog16622014.
APA：
Liu, L.,He, Y.,Li, Z.&Zhang, L..(2014).Application of two-dimensional echocardiography combined with enhanced flow in diagnosing fetal heart malformation.CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY,41,(2)
MLA：
Liu, L.,et al."Application of two-dimensional echocardiography combined with enhanced flow in diagnosing fetal heart malformation".CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY 41..2(2014):195-201
