Objective: To identify the relationship between the impaired baseline cerebral perfusion and the incidence of postoperative cognitive dysfunction (POCD) after off-pump coronary artery bypass grafting (OPCABG). Methods and Results: It is a single-institution, university hospital, prospective cohort study.A total of 364 patients scheduled for isolated OPCABG. Three hundred and twenty-row dynamic volume CT was performed each patient before surgery to determine if the cerebral perfusion was impaired. Each patient was evaluated with Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) 24 hours before and 7 days after surgery. The incidence of POCD was compared between the patients with impaired cerebral perfusion and those without impaired cerebral perfusion. Among the 364 patients, 76 patients (20.8%) were found to have impaired cerebral perfusion and they had a higher rate of POCD compared with the counterparts (26.3% VS 9.7%, P<.001). Multivariate logistic regression showed that impaired baseline cerebral perfusion was an independent risk factor for POCD after OPCABG (OR=3.40, 95%CI:1.57-7.35). Conclusions: Impaired baseline cerebral perfusion is an independent risk factor for POCD after OPCABG.
语种：
外文
中科院(CAS)分区：
出版当年[2013]版：
大类|4 区医学
小类|4 区心脏和心血管系统
最新[2025]版：
无
第一作者：
第一作者机构：[1]Beijing Anzhen Hospital, Capital Medical University, Department of Neurology, Beijing, China
推荐引用方式(GB/T 7714)：
Bi Q,Zhang W.-W,Li J.-Y,et al.Relationship between impaired baseline cerebral perfusion and cognitive dysfunction after off-pump coronary artery bypass grafting[J].2014,20(1):
APA：
Bi, Q,Zhang, W.-W,Li, J.-Y&Wu, H.(2014).Relationship between impaired baseline cerebral perfusion and cognitive dysfunction after off-pump coronary artery bypass grafting.,20,(1)
MLA：
Bi, Q,et al."Relationship between impaired baseline cerebral perfusion and cognitive dysfunction after off-pump coronary artery bypass grafting". 20..1(2014)
