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Successful Treatment of Multiple Small-Intestinal Perforations Caused by Epstein-Barr Virus-Positive Malignant Lymphoma in a Child

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机构： [1]Department of Pediatric Oncology Surgery, Children’s Hospital Affiliated of Zhengzhou University, Zhengzhou 450018, China [2]Department of Pediatric Oncology Surgery, National Center for Children’s Health, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China [3]Department of Pathology, Children’s Hospital Affiliated of Zhengzhou University, Zhengzhou 450018, China

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关键词： Children Epstein-Barr virus Intestine Lymphoma Perforation

摘要：

Multiple small-intestinal perforations caused by Epstein-Barr virus-positive malignant lymphoma in children are rare in clinical practice. This article reports the case of a 17-month-old girl with multiple small-intestinal perforations caused by Epstein-Barr virus-positive malignant lymphoma. Closure of perforations was done, and severely involved intestine was resected. Pathological examination of the lesions showed Epstein-Barr virus-positive diffuse large B cell lymphoma (DLBCL). This patient recovered from the operation uneventfully and received a six-cycle regimen of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone combination chemotherapy. For multiple perforation of the digestive tract, it is necessary to carefully explore and suture during the operation. In addition, pediatric DLBCL required timely chemotherapy after surgery. © 2020, Association of Surgeons of India.

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出版当年[2019]版：

大类 | 4 区医学

小类 | 4 区外科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区外科

第一作者：

第一作者机构： [1]Department of Pediatric Oncology Surgery, Children’s Hospital Affiliated of Zhengzhou University, Zhengzhou 450018, China

通讯作者：

通讯机构： [1]Department of Pediatric Oncology Surgery, Children’s Hospital Affiliated of Zhengzhou University, Zhengzhou 450018, China

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