Prevalence and risk factors for dyslipidemia among adults in rural and urban China: findings from the China National Stroke Screening and prevention project (CNSSPP)
机构：[1]Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science andTechnology, No.13 Hangkong Road, Wuhan 430030, China[2]Department of Internal Medicine, SUNY Upstate Medical University, New York, USA[3]Department of Internal Medicine, East Tennessee State University, JohnsonCity, Tennessee, USA[4]Department of Neurology, Tianjin Huanhu Hospital,Tianjin, China[5]Department of Neurosurgery, Xuanwu Hospital, Capitalmedical University, Beijing, China神经科系统神经外科首都医科大学宣武医院[6]Department of Neurology, ShenzhenSecond People’s Hospital, Shenzhen University, Shenzhen, Guangdong,China深圳市康宁医院深圳医学信息中心
BackgroundDyslipidemia is a modifiable risk factor for cardiovascular disease (CVD). We investigated the prevalence and associated risk factors of dyslipidemia- raised total cholesterol (TC), raised triglycerides (TG), raised low-density lipoprotein (LDL-C), low high-density lipoprotein (HDL-C), and raised non-high-density lipoprotein (non-HDL-C) in rural and urban China.MethodsWe analyzed data from 136,945 participants aged 40-100years of the CNSSPP project for 2014. Dyslipidemia was defined by the NCEP-ATP III and the 2016 Chinese guidelines for the management of dyslipidemia in adults. Complete data on demographic, metabolic and lifestyle characteristics were used. Chi-square tests and multivariable logistic regression were used to obtain age- and sex-adjusted prevalence and risk factors for dyslipidemia among participants.ResultsA total of 53.1% participants lived in rural areas. The prevalence of dyslipidemia was similar among rural and urban participants (43.2% vs. 43.3%). Regarding the components of dyslipidemia: urban compared with rural participants had a higher prevalence of low HDL-C (20.8% vs. 19.2%), whereas the prevalence of raised LDL-C (7.8% vs. 8.3%), raised TC (10.9% vs.11.8%) and raised non-HDL-C (10.0% vs. 10.9%) were lower in urban residents, (all p <0.001). Women were more likely to have raised TC than men (adjusted OR [AOR] =1.83, 95% confidence interval [CI]:1.75-1.91), raised LDL-C (AOR=1.55, 95% CI: 1.47-1.63) and high non-HDL-C (AOR=1.52 95% CI: 1.45-1.59) (all p <0.001). Compared with rural, urban participants had higher odds of dyslipidemia: low HDL-C (AOR=1.04, 95% CI: 1.01-1.07), and raised TG (AOR=1.06, 95% CI: 1.04-1.09). Hypertension and current drinker were less likely to get low HDL-C with AOR 0.93 (95% CI: 0.90-0.96) and AOR 0.73 (95% CI: 0.70-75), respectively. Overweight, obesity, central obesity and diabetes had higher odds of all dyslipidemias (p <0.001).ConclusionsLow HDL-C was higher in urban areas, whereas the remaining dyslipidemia types were more common in rural areas. Dyslipidemia was more common in women in both areas of residence. Overweight, obesity, central obesity and diabetes were associated with dyslipidemias. The need to intensify intervention programs to manage dyslipidemia and risk factors should be prioritized.
基金：
Ministry of Finance of the People's Republic of China [61]; Innovation Committee of Shenzhen Science and Technology [KJYY20170413162318686]; Fundamental Research Funds for the Central Universities, Huazhong University of Science and Technology, Wuhan, China [2016YXMS215]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2018 M630870]
第一作者机构：[1]Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science andTechnology, No.13 Hangkong Road, Wuhan 430030, China
通讯作者：
推荐引用方式(GB/T 7714)：
Opoku Sampson,Gan Yong,Fu Wenning,et al.Prevalence and risk factors for dyslipidemia among adults in rural and urban China: findings from the China National Stroke Screening and prevention project (CNSSPP)[J].BMC PUBLIC HEALTH.2019,19(1):doi:10.1186/s12889-019-7827-5.
APA：
Opoku, Sampson,Gan, Yong,Fu, Wenning,Chen, Dajie,Addo-Yobo, Emmanuel...&Lu, Zuxun.(2019).Prevalence and risk factors for dyslipidemia among adults in rural and urban China: findings from the China National Stroke Screening and prevention project (CNSSPP).BMC PUBLIC HEALTH,19,(1)
MLA：
Opoku, Sampson,et al."Prevalence and risk factors for dyslipidemia among adults in rural and urban China: findings from the China National Stroke Screening and prevention project (CNSSPP)".BMC PUBLIC HEALTH 19..1(2019)
医学