机构：[1]Emergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China[2]Emergency Department, China-Japan Friendship Hospital, Beijing, China[3]Emergency Department, Xuanwu Hospital Capital Medical University, Beijing, China内科系统急诊科首都医科大学宣武医院[4]Emergency Department, Peking University First Hospital, Beijing, China[5]Emergency Department, Shandong Provincial Hospital, Jinan, Shandong, China[6]Emergency Department, Tianjin Medical University General Hospital, Tianjin, China[7]Emergency Department, The First Hospital of China Medical University, Shenyang, Liaoning, China[8]Emergency Department, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China中山大学附属第一医院[9]Emergency Department, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China[10]Emergency Department, Tianjin Third Central Hospital, Tianjin, China[11]Emergency Department, Guangdong Provincial People’s Hospital, Guangzhou, Guangdong, China[12]Emergency Department, Xijing Hospital, Air Force Medical University, Xi’an, Shaanxi, China[13]Emergency Department, Shanxi Provincial People’s Hospital, Xi’an, Shaanxi, China[14]Emergency Department, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
This retrospective multicentre observational study was performed to assess the predictors of acute kidney injury (AKI) in patients with acute decompensated heart failure (ADHF) in emergency departments in China.In total, 1743 consecutive patients with ADHF were recruited from August 2017 to January 2018. Clinical characteristics and outcomes were compared between patients with and without AKI. Predictors of AKI occurrence and underdiagnosis were assessed in multivariate regression analyses.Of the 1743 patients, 593 (34.0%) had AKI. AKI was partly associated with short-term all-cause mortality and cost. Cardiovascular comorbidities such as coronary heart disease, diabetes mellitus, and hypertension remained significant predictors of AKI in the univariate analysis. AKI was significantly more likely to occur in patients with a lower arterial pH, lower albumin concentration, higher creatinine concentration, and higher N-terminal pro-brain natriuretic peptide (NT-proBNP) concentration. Patients treated with inotropic agents were significantly more likely to develop AKI during their hospital stay.This study suggests that cardiovascular comorbidities, arterial pH, the albumin concentration, the creatinine concentration, the NT-proBNP concentration, and use of inotropic agents are predictors of AKI in patients with ADHF.
基金：
This study
was supported by a grant from the Discovery
Cardiovascular Research Fund, Chinese
Medical Doctor Association, P.R. China.
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2020]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
最新[2023]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
JCR分区：
出版当年[2019]版：
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
最新[2023]版：
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
第一作者机构：[1]Emergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Emergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China[*1]Emergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing 100191, China.
推荐引用方式(GB/T 7714)：
Hongxia Ge,Yang Liang,Yingying Fang,et al.Predictors of acute kidney injury in patients with acute decompensated heart failure in emergency departments in China.[J].JOURNAL OF INTERNATIONAL MEDICAL RESEARCH.2021,49(9):doi:10.1177/03000605211016208.
APA：
Hongxia Ge,Yang Liang,Yingying Fang,Yi Jin,Wenting Su...&Qingbian Ma.(2021).Predictors of acute kidney injury in patients with acute decompensated heart failure in emergency departments in China..JOURNAL OF INTERNATIONAL MEDICAL RESEARCH,49,(9)
MLA：
Hongxia Ge,et al."Predictors of acute kidney injury in patients with acute decompensated heart failure in emergency departments in China.".JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 49..9(2021)
