详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Gender differences in prevalence and clinical correlates of anxiety symptoms in first-episode and drug-naïve patients with major depressive disorder.

107| 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE ◇ SSCI

作者：

机构： [1]The Mental Health Center, Yunnan University, Kunming, China [2]School of Ethnology and Sociology Yunnan University, Kunming, China [3]Neurology Department, Xuan Wu Hospital of Capital Medical University, Beijing, China [4]Qingdao Mental Health Center, Qingdao University, Qingdao, China [5]Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA [6]Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China [7]CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China [8]Department of Psychology, University of Chinese Academy of Sciences, Beijing, China

出处：

DOI：

ISSN：

关键词： Gender differences Major depressive disorder (MDD) Comorbid anxiety with major depressive disorder First episode and drug naïve (FEDN) patients

摘要：

Gender differences in major depressive disorder (MDD) are commonly reported; however, gender differences in first-episode and drug-naïve (FEDN) patients with major depressive disorder remain unclear. This study aimed to examine potential gender differences in the prevalence and clinical correlates of comorbid anxiety in FEDN patients with MDD.A cross-sectional study was conducted with1718 FEDN patients with MDD. Patients' demographic and clinical data were collected and analyzed using standardized clinical evaluation forms. The Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA) and Positive and Negative Syndrome Scale (PANSS) were used to evaluate depression, anxiety and psychotic symptoms, respectively.There were no gender-based differences in the comorbidity rates of MDD and anxiety disorders (male: 10.2% vs. female:12.7%, P = 0.123). The prevalence of MDD with severe anxiety symptoms in male patients was similar to that of female patients (80.8%vs. 80.1%, P = 0.749). Male MDD patients were younger, had earlier age of onset, and were less likely to be married. In both the male and female groups, HAMD scores, HAMA scores, suicide attempts, and psychotic symptoms in patients with severe anxiety symptoms were higher than those patients without severe anxiety symptoms (all p ≤ 0.001). Furthermore, binary logistic regression analysis showed that psychotic symptoms and suicide attempts significantly predicted severe anxiety symptoms in both male and female patients with MDD, while body mass index(BMI)significantly predicted severe anxiety symptoms in MDD females only.Our study showed that there were no gender differences in the prevalence of comorbid anxiety in FEDN patients with MDD. Suicide attempts and psychiatric symptoms were associated with severe anxiety symptoms in both men and women with MDD, whereas BMI was only correlated with severe anxiety symptoms in women.Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2020]版：

大类 | 3 区医学

小类 | 4 区精神病学

最新[2023]版：

大类 | 2 区医学

小类 | 2 区精神病学

JCR分区：

出版当年[2019]版：

Q2 PSYCHIATRY

最新[2023]版：

Q1 PSYCHIATRY

影响因子： 4.3 最新[2023版] 4.7 最新五年平均 2.567 出版当年[2019版] 2.738 出版当年五年平均 2.586 出版前一年[2018版] 3.735 出版后一年[2020版]

第一作者：

第一作者机构： [1]The Mental Health Center, Yunnan University, Kunming, China [2]School of Ethnology and Sociology Yunnan University, Kunming, China

通讯作者：

通讯机构： [7]CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China [8]Department of Psychology, University of Chinese Academy of Sciences, Beijing, China [*1]Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, Beijing 100101, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

Gender differences in prevalence and clinical correlates of anxiety symptoms in first-episode and drug-naïve patients with major depressive disorder.

文献详情

相关文献