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The safety and efficacy of Ezetimibe Plus Statins on ASVD and Related Diseases.

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机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China [3]Department of China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China [4]Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, USA
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关键词: ezetimibe statin atherosclerotic vascular disease

摘要:
It is well known that atherosclerotic vascular disease (ASVD) in the elderly is a global disease with high morbidity, mortality and disability, and plasma LDL-C correction is the most important strategy for ASVD control. However, a large proportion of patients failed to achieve their ideal LDL-C goals after statins use. Ezetimibe, a newly non-statin lipid-lowering agent, is an inhibitor of exogenous cholesterol absorption. Whereby, ezetimibe plus statins may reduce LDL-C more strongly than statins alone. Differed from any other papers published previously, which only involved ezetimibe plus statins for coronary heart disease, the highlight of this paper is to summarize the efficacy and safety of ezetimibe plus statins in all kinds of ASVD subtypes and their related diseases, mainly included aortic atherosclerosis, coronary artery disease, cerebrovascular and peripheral artery diseases. Obviously, this paper is inimitable, which will provide the readers an important reference, especially in treating the elderly with multi-organs atherosclerosis.Copyright: © 2021 Wan et al.

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出版当年[2020]版:
大类 | 2 区 医学
小类 | 2 区 老年医学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 老年医学
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出版当年[2019]版:
Q1 GERIATRICS & GERONTOLOGY
最新[2023]版:
Q1 GERIATRICS & GERONTOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

第一作者:
第一作者机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China [3]Department of China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China
通讯作者:
通讯机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China [3]Department of China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China [*1]Xuanwu Hospital, Capital Medical University, Beijing, 100053, China
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