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Gender- and age-based differences in outcomes of mechanically ventilated ICU patients: a Chinese multicentre retrospective study.

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机构： [1]Department of Critical Care Medicine, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China. [2]Department of Critical Care Medi‑cine, Fu Xing Hospital, Capital Medical University, No.20 Fuxingmenwai Street, Xicheng District, Beijing 100038, China. [3]Department of Critical Care Medicine, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China.

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关键词： Gender Age Mechanical ventilation Intensive care unit Outcome Mortality

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Previous studies have suggested that the gender and/or age of a patient may influence the clinical outcomes of critically ill patients. Our aim was to determine whether there are gender- and age-based differences in clinical outcomes for mechanically ventilated patients in intensive care units (ICUs).We performed a multicentre retrospective study involving adult patients who were admitted to the ICU and received at least 24 h of mechanical ventilation (MV). The patients were divided into two groups based on gender and, subsequently, further grouped based on gender and age < or ≥ 65 years. The primary outcome measure was hospital mortality.A total of 853 mechanically ventilated patients were evaluated. Of these patients, 63.2% were men and 61.5% were ≥ 65 years of age. The hospital mortality rate for men was significantly higher than that for women in the overall study population (P = 0.042), and this difference was most pronounced among elderly patients (age ≥ 65 years; P = 0.006). The durations of MV, ICU lengths of stay (LOS), and hospital LOS were significantly longer for men than for women among younger patients (P ≤ 0.013) but not among elderly patients. Multivariate logistic regression analysis revealed that male gender was independently associated with hospital mortality among elderly patients but not among younger patients.There were important gender- and age-based differences in the outcomes among mechanically ventilated ICU patients. The combination of male gender and advanced age is strongly associated with hospital mortality.© 2022. The Author(s).

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出版当年[2021]版：

大类 | 4 区医学

小类 | 4 区麻醉学

最新[2025]版：

大类 | 3 区医学

小类 | 3 区麻醉学

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出版当年[2020]版：

Q4 ANESTHESIOLOGY

最新[2023]版：

Q2 ANESTHESIOLOGY

影响因子： 2.3 最新[2023版] 2.6 最新五年平均 2.217 出版当年[2020版] 2.477 出版当年五年平均 1.695 出版前一年[2019版] 2.376 出版后一年[2021版]

第一作者：

第一作者机构： [1]Department of Critical Care Medicine, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China. [2]Department of Critical Care Medi‑cine, Fu Xing Hospital, Capital Medical University, No.20 Fuxingmenwai Street, Xicheng District, Beijing 100038, China.

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